Planta Med 2012; 78 - PJ9
DOI: 10.1055/s-0032-1321169

Anthraquinone chemical fingerprint: Madagascin from the fruits of Rhamnus L. Spp.

G Carlucci 1, F Epifano 1, S Genovese 1, D Kremer 2, M Locatelli 1
  • 1Dipartimento di Scienze del Farmaco, Università degli Studi ''G. d'Annunzio'' Chieti-Pescara, Via dei Vestini 31, 66100 Chieti (CH), Italy
  • 2Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, 10000 Zagreb, Croatia

Prenylation is the chemical or enzymatic addition of a terpenyl moiety to an accepting molecule that occurs in nature in plant families like Rutaceae, Asteraceae, Apiaceae, Clusiaceae, Fabaceae. As a continuation of our studieswe report herein the determination of madagascin from the fruits of Rhamnus cathartica L., R. fallax Boiss., R. intermedia Steud. & Hochst., and R. rupestris Royle. The title compound is described for the first time as a component of fruit extracts and is noteworthy to underline that this compound was found only in Rhamnus cathartica L. and R. intermedia Steud. & Hochst., at 14.31 and 4.63µg/g of fruit (dry weight), respectively.