Phytochemistry of Dioscorea villosa

Z Ali; IA Khan

doi:10.1055/s-0032-1321115

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Planta Med 2012; 78 - PI428
DOI: 10.1055/s-0032-1321115

Phytochemistry of Dioscorea villosa

Z Ali ¹, IA Khan ¹^,²

¹National Center for Natural Products Research
²Department of Pharmacognosy, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, MS 38677, USA

Congress Abstract

Dioscorea plants are mostly known for their spirostane and furostane steroid glycosides, particularly for diosgenin-base glycosides. Dioscorea villosa root, a wild yam, was investigated for new chemical constituents and two new cholestane (1 and 2) and several known spirostane and furostane steroid glycosides were isolated. The structures of the isolated compounds were established using spectroscopic techniques and chemical methods.

Acknowledgement: The work was supported by NIH (NIH Prime award number 1P50AT006268–01) and FDA (Specific Cooperative Research Agreement Number U01 FD004246–01).