in vivo anthelmintic activity of Syzygium cumini leaves against Haemonchus contortus in sheep

The gastrointestinal parasitism is currently considered the biggest health problem faced by producers worldwide. Haemonchus contortus is a parasite of small ruminants that is responsible for major losses. Many plants are known as having anthelmintic activity, however, their effects requiring verification. In this study, “Santa Inês” breed sheep were fed with leaves powder of Syzygium cumini, which was dried at 37°C. This powder was added to animal feed (1,2g/kg). The sheep weight, fecal egg counts per gram (EPG) and blood test were analyzed in the 1^th, 7^th and 14^th day. Chemical and bromatology evaluation of powder of leaves was done. A reduction of 76,67% in EPG was observed in the 14^th day. Seven days after treatment, EPG redution of 17,8% was yet observed. The amount of total phenolics compounds was 156,13g tannic acid/kg of dry matter. The levels of protein and minerals contained on leaves was 9,1% and 45,8g/Kg, respectively, in contrast with 21,61% and 57,36g/Kg of feed. After 14 days, moderate weight gain was observed (3%) and the blood test showed decrease on eosinophils levels in animal treated. It is concluded that the S. cumini leaves showed anthelmintic activity when administered together with feed and a discrete weight gain was observed.