Planta Med 2012; 78 - PI412
DOI: 10.1055/s-0032-1321099

Quantitative determination of casticin in Turkish samples of Vitex agnus-castus

G Gülsoy 1, E Eroğlu Özkan 1
  • 1Istanbul University, Faculty of Pharmacy, Department of Pharmacognosy, 34116 Beyazit/Istanbul, Turkey

Vitex agnus-castus (Verbenaceae) is a widely distributed small tree in Turkish coastal areas. The fruits of this plant have long been used as a traditional medicine for the treatment of gynecological problems in Anatolia. In our previous study, the essential oil compositions of Vitex agnus-castus fruits collected from five different regions were identified by GC/GC-MS. In this study, quantitative analyses of casticin in the methanolic extracts of fruits of the same five samples of Vitex agnus castus were determined by HPLC according to the European Pharmacopoeia 2007. The results have shown that the amount of casticin determined in the fruits of Turkish samples of Vitex agnus-castus is compatible with the European Pharmacopoeia standards.