Planta Med 2012; 78 - PI409
DOI: 10.1055/s-0032-1321096

Coumarins from the aerial parts of Lomatopodium staurophyllum

M Malmir 1, 2, AR Gohari 1, S Saeidnia 1, Y Ajani 3
  • 1Medicinal Plants Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  • 2iMed.UL, Faculty of Pharmacy, University of Lisbon, Av. Professor Gama Pinto, 1649–019 Lisbon, Portugal
  • 3Institute of Medicinal Plants, ACECR, Tehran, Iran

The genus Lomatopodium Fisch.& C.A.Mey, well-known as Pa-pahn in Persian language, includes one endemic species spread throughout North-East and Northern parts of Iran. Here, we focused on the isolation and identification of the main coumarins from the aerial parts of L. staurophyllum which has not been previously reported. Three new compounds, 4'-acetyl-cis-khellactone (10), 3'-acetyl-cis-khellactone (11) and 3'-isovaleroyl-cis-khellactone (13), together with Pteryxin (1), Corymbocoumarin (2), Anomalin (3), Isosamidin (4), Samidin (5), Bergapten (6), cis-Khellactone (7), d-Laserpitin (8), 3'-angeloyl-cis-khellactone (9), 4'-isovaleroyl-cis-khellactone (12), Hamaudol (14) and Decursinol (15) were the main coumarins identified.