Evaluation of carajurin content and stability of spray-dried Arrabidaea chica extract using different gum as wall material

Arrabidaea chica (bignoniaceae) populary Known as Carajuru is widely distributed in South America tropical forest. Anti-inflammatory, astringent agents, among other uses have been described in traditional medicine (Devia et al.2002) for this species. Previous reports demonstrated that Carajurin (6,7-dihydroxy-5,4-dimethoxy-flavylium) and other anthocyanins are involved with the pharmacological activity. These compounds are easily decomposed with high temperatures, humidity and oxygen. Therefore this study evaluated the stability of spray-dried A.chica extract employing different core materials. Three different homogeinizaded wall material (arabic gum, cashew gum and mixture Arabic gum/maltodextrin 1/1) were tested. The extracts were processed in Spray Drier Büchi B 290 temperature 160°C, N₂ flow rate at 35m³/h. 2,2mm-diameter. The samples were stored in different types of packages (glass, plastic, aluminum) in stability chambers with 75% humidity and 40°C during 90 days. The aglycone ratio was maintained in the Arabic gum wall material, whereas for 1:1 Arabic gum/maltodextrin wall material, 90% of the aglycone were lost as determined by HPLC-DAD and ESI-MS with direct infusion, Phenomenex Gemini C-18 column (4,6mm x 250mm i.d., 3µm), flow rate 1 mL/min, mobile phase methanol: aqueous phosphoric acid (pH 2.00) gradient elution.