Pharmacological screening of medicinal plants for anti cancer, anti inflammatory and anti diabetic activities

M Yaseen; S Bahaffi; H Kigoshi; M Kita

doi:10.1055/s-0032-1321049

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Planta Med 2012; 78 - PI362
DOI: 10.1055/s-0032-1321049

Pharmacological screening of medicinal plants for anti cancer, anti inflammatory and anti diabetic activities

M Yaseen ¹, S Bahaffi ¹, H Kigoshi ², M Kita ²

¹Department of Chemistry, Faculty of Science, University of Tabuk,71491 Tabuk, Kingdom of Saudi Arabia
²Department of Chemistry, Graduate School of Pure and Applied Science, University of Tsukuba, Japan

Congress Abstract

We report a detailed Pharmacological Screening of 11 Medicinal plants (36 samples) growing in Tabuk region of Saudi Arabia for Cytotoxicity against HeLa S3 Cells, Anti-inflammatory activity (Raw cells) and Adipogenesis. Three plant samples were found Cytotoxic against HeLa S3 cells namely Commiphora Africana (16.9%), Raetam ratam plant (8.2%), Raetam ratam root (3.8%). Six plant samples were found active as Anti-infammatory namely Artemisa seberi (28–0%), Commiphora africana (6–3%), Raetam ratam (20–6%), Citrullus colocynthsis plant (33.7%), Citrullus colocynthsis seed (40–1%), Ocimum bacillum (45.4%). Three plant samples were found with inhibitory effect on Adipogenesis namely Citrullus colocynthsis, Raetam ratam and Fagonia indica. We have also isolated several biomolecules responsible for all the three activities mentioned above, which will be presented.