Planta Med 2012; 78 - PI350
DOI: 10.1055/s-0032-1321037

Secondary metabolites from the aerial parts of Centaurea pannonica

T Milošević-Ifantis 1, 2, D Muratspahić-Pavlović 2, S Solujić 2, H Skaltsa 1
  • 1Department of Pharmacognosy & Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis, Zografou, 157 71, Athens, Greece
  • 2Faculty of Science, University of Kragujevac, Radoja Domanovića 12, 34000 Kragujevac, Serbia

Further investigation of Centaurea pannonica (Heuffel) Simonkai [collected in Šumadija region-Serbia, on September 2008], afforded the new sesquiterpene lactone (1), compound 2, previously described, as well as eleven known guaianolides, namely, babylin A, babylin B, chlorohyssopifolin C, repin, repdiolide, epoxy-repdiolide, chlororepdiolide, cebellin J, janerin, 19-deoxyjanerin, rhaposerine, three known lignans arctigenin, matairesinol, arctiin, three known flavonoids, apigenin, hispidulin, diosmetin and one known phenyl propanoid glucoside, syringine. The presence of guaianolides is characteristic feature of Centaurea taxa belonging to the section Jacea, where is classified C. pannonica [2, 3].