Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000058.xml
Planta Med 2012; 78 - PI309
DOI: 10.1055/s-0032-1320996
DOI: 10.1055/s-0032-1320996
Isolation of new sesquiterpene lactones from Inula britannica with centrifugal partition chromatography
Inula britannica produces a variety of biologically active sesquiterpene lactones mainly pseudoguaianolides and seco-eudesmanolides. In order to further study the chemical constituents of I. britannica we used centrifugal partition chromatography followed by semi-preparative HPLC to isolate 10 sesquiterpene lactones. Three new seco-eudesmanolides (1–3) were isolated in the course of these experiments. The structure elucidation of these compounds was accomplished with high resolution MS, 1H-NMR, 13C-NMR, COSY, HSQC, HMBC, and NOESY.