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Planta Med 2012; 78 - PI287
DOI: 10.1055/s-0032-1320974
DOI: 10.1055/s-0032-1320974
Indole alkaloids from Duroia macrophylla (Rubiaceae)
Duroia macrophylla Huber (Rubiaceae) is a tropical tree, known as “puruí”, which occurs in the Amazon region. The study of the methnolic extract led to the isolation of the indolic alkaloids 9-methoxyajmalicine and 10-methoxyajmalicine (cabucine) which were identified by NMR and MS data analyses. The methanolic extract was toxic against Artemia salina (IC50=40µg/mL).