Planta Med 2012; 78 - PI186
DOI: 10.1055/s-0032-1320874

A new isoflavone glucoside from Blepharis ciliaris

MA El-Shanawany 1, HM Sayed 1, SRM Ibrahim 1, MAA Fayed 1, MM Radwan 2, SA Ross 2, 3
  • 1Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt
  • 2National Center for Natural Products Research,
  • 3Department of Pharmacognosy, University of Mississippi, School of Pharmacy, University 38677, USA

Phytochemical study of the aerial parts of Blepharis ciliaris. led to the isolation of one new isoflavone glucoside [ genstein-7-O-(6''-O-E-caffeoyl-β-D-glucopyranoside)] (1), along with seven known compounds: methyl veratrate, methyl vanillate, protocatechuic acid, naringenin-7-O-(3''-acetyl-6''-E-p-coumaroyl-β-D-glucopyranoside), naringenin-7-O-(6''-E-p-coumaroyl-β-D-glucopyranoside), api-genin-7-O-(6''-E-p-coumaroyl-β-D- glucopyranoside), and acteoside. Their structures were established on the basis of detailed analyses of chemical, and spectral data. The antioxidant activity was evaluated.