Copper-Impregnated Magnetite as a Heterogeneous Catalyst for the Homocoupling of Terminal Alkynes

Juana M. Pérez; Rafael Cano; Miguel Yus; Diego J. Ramón

doi:10.1055/s-0032-1316872

Synthesis, Table of Contents

Synthesis 2013; 45(10): 1373-1379
DOI: 10.1055/s-0032-1316872

paper

Copper-Impregnated Magnetite as a Heterogeneous Catalyst for the Homocoupling of Terminal Alkynes

Juana M. Pérez

Departamento Química Orgánica and Instituto de Síntesis Orgánica, Universidad de Alicante, Apdo. 99, 03080 Alicante, Spain Fax: +34(96)5903549 Email: djramon@ua.es

,

Rafael Cano

Departamento Química Orgánica and Instituto de Síntesis Orgánica, Universidad de Alicante, Apdo. 99, 03080 Alicante, Spain Fax: +34(96)5903549 Email: djramon@ua.es

,

Miguel Yus

Departamento Química Orgánica and Instituto de Síntesis Orgánica, Universidad de Alicante, Apdo. 99, 03080 Alicante, Spain Fax: +34(96)5903549 Email: djramon@ua.es

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Diego J. Ramón*

Departamento Química Orgánica and Instituto de Síntesis Orgánica, Universidad de Alicante, Apdo. 99, 03080 Alicante, Spain Fax: +34(96)5903549 Email: djramon@ua.es

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Abstract

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Abstract

Copper-impregnated magnetite is a versatile heterogeneous catalytic system for the synthesis of 1,3-diynes by the homocoupling of terminal alkynes. This catalyst does not require the use of pressurized oxygen as the oxidant and it does not need a solvent or harsh conditions to give the expected products. Moreover, the catalyst can be removed from the reaction medium simply by using a magnet. The reaction occurs at the lowest copper loading reported for any heterogeneous catalyst.

Key words

alkynes - copper - heterogeneous catalysis - iron - supported catalysis - coupling - furans

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References

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