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Int J Sports Med 2013; 34(03): 207-213
DOI: 10.1055/s-0032-1312627
Training & Testing
© Georg Thieme Verlag KG Stuttgart · New York

Molecular Adaptations to Concurrent Training

E. O. de Souza
1   Department of Sport, School of Physical Education and Sport, University of São Paulo, SP, Brazil
,
V. Tricoli
1   Department of Sport, School of Physical Education and Sport, University of São Paulo, SP, Brazil
,
H. Roschel
1   Department of Sport, School of Physical Education and Sport, University of São Paulo, SP, Brazil
,
P. C. Brum
1   Department of Sport, School of Physical Education and Sport, University of São Paulo, SP, Brazil
,
A.V. N. Bacurau
1   Department of Sport, School of Physical Education and Sport, University of São Paulo, SP, Brazil
,
J.C. B. Ferreira
1   Department of Sport, School of Physical Education and Sport, University of São Paulo, SP, Brazil
6   Stanford University School of Medicine, CA, USA
,
M. S. Aoki
2   School of Arts, Sciences, Humanities, University of São Paulo, SP, Brazil
,
M. Neves-Jr
3   School of Medicine, University of São Paulo, SP, Brazil
,
A. Y. Aihara
4   Diagnósticos das Américas S/A (DASA), SP, Brazil
,
A. da Rocha Correa Fernandes
5   Department of Radiology of Federal University of São Paulo, SP, Brazil
,
C. Ugrinowitsch
1   Department of Sport, School of Physical Education and Sport, University of São Paulo, SP, Brazil
› Author Affiliations
Further Information

Publication History



accepted after revision 17 April 2012

Publication Date:
08 October 2012 (online)

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Abstract

This study investigated the chronic effects of concurrent training (CT) on morphological and molecular adaptations. 37 men (age=23.7±5.5 year) were divided into 4 groups: interval (IT), strength (ST) and concurrent (CT) training and a control group (C) and underwent 8 weeks of training. Maximum strength (1RM) and muscle cross-sectional area (CSA) were evaluated before and after training. Muscle samples were obtained before the training program and 48 h after the last training session. VO2max improved in 5±0.95% and 15±1.3% (pre- to post-test) in groups CT and IT, respectively, when compared to C. Time to exhaustion (TE) improved from pre- to post-test when compared to C (CT=6.1±0.58%; IT=8.3±0.88%; ST=3.2±0.66%). 1RM increased from pre-to post-test only in ST and CT groups (ST=18.5±3.16%; CT=17.6±3.01%). Similarly, ST and CT groups increased quadriceps CSA from pre-to post-test (6.2±1.4%; 7.8±1.66%). The p70S6K1 total protein content increased after CT. The ST group showed increased Akt phosphorylation at Ser473 (45.0±3.3%) whereas AMPK phosphorylation at Thr172 increased only in IT group, (100±17.6%). In summary, our data suggest that despite the differences in molecular adaptations between training regimens, CT did not blunt muscle strength and hypertrophy increments when compared with ST.

Key words

maximum dynamic strength - muscle hypertrophy - interval training
 

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