Primary Ewing's Sarcoma of the Ethmoid Sinus with Intracranial and Orbital Extension: Case Report and Literature Review

Ewing's sarcoma family of tumors (ESFTs) is a group of cancers that commonly arises in patients during their second decade of life. It frequently involves the trunk and long bones of the body with primary Ewing's sarcoma of the paranasal sinuses being exceedingly rare. We describe a case of a 39-year-old woman with primary Ewing's sarcoma (ES) originating from the ethmoid sinuses with intracranial extension into the anterior cranial fossa and the orbit. CT, MRI and histopathological findings will also be included. There are very few case reports on primary Ewing's sarcoma originating from the ethmoid sinuses, and to our knowledge, this is the second reported case with the involvement of the anterior cranial fossa. However, this is the only case where immunochemical staining and molecular genetic analysis are available for definitive diagnosis.