Semin Reprod Med 2012; 30(02): 077-083
DOI: 10.1055/s-0032-1307415
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Consequences of Superovulation and ART Procedures

Rachel Weinerman
1   Department of Obstetrics and Gynecology, NYU School of Medicine, New York
,
Jamie Grifo
2   NYU Fertility Center, New York, New York
› Author Affiliations
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Publication History

Publication Date:
27 April 2012 (online)

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Abstract

Superovulation procedures and assisted reproductive technologies (ART) have provided the means for significant improvement in infertility care. Although generally safe, these procedures are associated with complications that, albeit rare, can have significant morbidity. Complications from superovulation include ovarian hyperstimulation syndrome, thromboembolism, and adnexal torsion. Complications from oocyte retrieval include infection, bleeding, bowel injury, and anesthetic complications. Early pregnancy complications from in vitro fertilization include multiple gestations, ectopic pregnancy, and heterotopic pregnancy. Stimulation, retrieval, and transfer techniques can be modified to minimize these risks and prevent complications. Further research in the field is needed to continue to improve the safety of superovulation and ART.