Semin Neurol 2012; 32(01): 051-054
DOI: 10.1055/s-0032-1306386
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Lysosomal Disorders Associated with Leukoencephalopathy

Deborah L. Renaud
1   Departments of Neurology and Pediatrics, Mayo Clinic, Rochester, Minnesota
› Author Affiliations
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Publication History

Publication Date:
15 March 2012 (online)

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Abstract

Metachromatic leukodystrophy and Krabbe's disease are among the most widely recognized causes of leukodystrophy. However, white matter changes have been described in several other lysosomal storage disorders. These conditions are summarized and those associated with hypomyelination are reviewed in more detail.