Semin Neurol 2012; 32(01): 029-033
DOI: 10.1055/s-0032-1306383
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Clinical Approach to Leukoencephalopathies

Deborah L. Renaud
1   Departments of Neurology and Pediatrics, Mayo Clinic, Rochester, Minnesota
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Publikationsdatum:
15. März 2012 (online)

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Abstract

Recent advances in biochemical and molecular genetics have led to the discovery of new leukoencephalopathies. Despite these advances, many patients with leukoencephalopathy remain undiagnosed. A systematic approach to the investigation of these patients is needed to select the most appropriate testing strategy. In this article, the author presents a clinical and magnetic resonance imaging (MRI) based approach to the evaluation of patients with leukoencephalopathy.