Notfallmedizin up2date, Table of Contents Notfallmedizin up2date 2012; 7(2): 145-157DOI: 10.1055/s-0031-1298584 Spezielle Notfallmedizin Georg Thieme Verlag KG Stuttgart · New YorkErsttherapie polytraumatisierter Patienten mit Schädel-Hirn-Verletzung B. Donaubauer , F. Pfeifer , H. Wrigge Recommend Article Abstract Buy Article All articles of this category Full Text References Literatur 1 Deutsche Gesellschaft für Unfallchirurgie. DGU Traumaregister 2011. http://traumaregister.de/images/stories/downloads/jahresbericht_2011.pdf 2 Hokema F, Donaubauer B, Busch T et al. Initial management of polytraumatized patients in the emergency department. Anasthesiol Intensivmed Notfallmed Schmerzther 2007; 42: 716-723 3 Donaubauer B, Kerner T, Kaisers U. Fluid therapy – preclinical volume therapy in the management of polytrauma. Anasthesiol Intensivmed Notfallmed Schmerzther 2006; 41: 412-416 4 Graham DI, Adams JH. Ischemic brain damage in fatal injuries. Lancet 1971; 1: 256 5 Chi JH, Knudson MM, Vassar MJ et al. Prehospital hypoxia affects outcome in patients with traumatic brain injury: a prospective multicenter study. J Trauma 2006; 61: 1134-1141 6 Bernard SA, Nguyen V, Cameron P et al. Prehospital rapid sequence intubation improves functional outcome for patients with severe traumatic brain injury: a randomized controlled trial. Ann Surg 2010; 252: 959-965 7 Davis DP, Peay J, Sise MJ et al. The impact of pre-hospital endotracheal intubation on outcome in moderate to severe traumatic brain injury. J Trauma 2005; 58: 933 8 Elm E, Schoettker P, Henzi I et al. Pre-hospital tracheal intubation in patients with traumatic brain injury: systematic review of current evidence. Br J Anaesth 2009; 103: 371-386 9 Deutsche Gesellschaft für Unfallchirurgie. S3-Leitlinie Polytrauma. http://www.awmf.org/leitlinien/detail/ll/012-019.html 10 Davis DP, Peay J, Sise MJ et al. Prehospital airway and ventilation management: a trauma score and injury severity score-based analysis. J Trauma 2010; 69: 294-301 11 Coles JP, Minhas PS, Fryer TD et al. Effect of hyperventilation on cerebral blood flow in traumatic head injury: clinical relevance and monitoring correlates. Crit Care Med 2002; 30: 1950-1959 12 Diringer MN, Aiyagari V, Zazulia AR et al. Effect of hyperoxia on cerebral metabolic rate for oxygen measured using positron emission tomography in patients with acute severe head injury. J Neurosurg 2007; 106: 526-529 13 Turner J, Nicholl J, Webber L et al. A randomised controlled trial of pre-hospital intravenous fluid replacement therapy in serious trauma. Health Technology Assessment 2000; 4: 1-57 14 James MF, Michell WL, Joubert IA et al. Resuscitation with hydroxyethyl starch improves renal function and lactate clearance in penetrating trauma in a randomized controlled study: the FIRST trial (Fluids in Resuscitation of Severe Trauma). Br J Anaesth 2011; 107: 693-702 15 Cooper DJ, Myles PS, McDermott FT et al. Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury: a randomized controlled trial. JAMA 2004; 291: 1350-1357 16 Bulger EM, May S, Brasel KJ et al. Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial. JAMA 2010; 304: 1455-1464 17 Deutsche Gesellschaft für Neurochirurgie. S2-Leitlinie „Schädel-Hirn-Trauma im Erwachsenenalter“. http://www.awmf.org/uploads/tx_szleitlinien/008-001m.pdf 18 Koerner I, Brambrink M. Brain protection by anesthetic agents. Curr Opin Anaesthesiol 2006; 19: 481-486 19 Schalen W, Sonesson B, Messeter K et al. Clinical outcome and cognitive impairment in patients with severe head injuries treated with barbiturate coma. Acta Neurochir 1992; 117: 153-159 20 Takeshita H, Okuda Y, Sari A. The effects of ketamine on cerebral circulation and metabolism in man. Anesthesiology 1972; 36: 69-75 21 Himmelseher S, Durieux M. Revising a dogma: ketamine for patients with neurological injury?. Anesth Analg 2005; 101: 524-534 22 Wakai A, Roberts I, Schierhout G. Mannitol for acute traumatic brain injury. Cochrane Database Syst Rev 2007; (1) CD001049 23 Sayre MR, Daily SW, Stern SA et al. Out-of-hospital administration of mannitol to head-injured patients does not change systolic blood pressure. Acad Emerg Med 1996; 3: 840-848 24 CRASH trial collaborators. Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial. Lancet 2004; 364: 1321-1328 25 Alderson P, Roberts I. Corticosteroids for acute traumatic brain injury. Cochrane Database Syst Rev 2005; (1) CD000196 26 Wright DW, Kellermann AL, Hertzberg VS et al. ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury. Ann Emerg Med 2007; 49: 391-402 27 Xiao G, Wei J, Yan W et al. Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial. Crit Care 2008; 12: R61 28 Temkin NR, Anderson GD, Winn HR et al. Magnesium sulfate for neuroprotection after traumatic brain injury: a randomised controlled trial. Lancet Neurol 2007; 6: 29-38 29 Shakur H, Roberts I, Bautista R et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010; 376: 23-32 30 CRASH-2 Collaborators, Intracranial Bleeding Study. Effect of tranexamic acid in traumatic brain injury: a nested randomised, placebo controlled trial (CRASH-2 Intracranial Bleeding Study). BMJ 2011; 343: d379