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Planta Med 2012; 78(10): 1010-1014
DOI: 10.1055/s-0031-1298539
Natural Product Chemistry
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

Sesquiterpenoids from the Rhizomes of Homalomena occulta

Xiao-Yu Xie
1   Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, PR China
2   Graduate University of Chinese Academy of Sciences, Beijing, PR China
,
Rui Wang
1   Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, PR China
,
Yan-Ping Shi
1   Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, PR China
› Author Affiliations
Further Information

Publication History

received 25 February 2012
revised 15 March 2012

accepted 16 April 2012

Publication Date:
09 May 2012 (online)

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Abstract

Phytochemical investigation on the rhizomes of Homalomena occulta resulted in the isolation of five new sesquiterpenoids, namely cadinane-4β,5α,10α-triol (1), 5(11)-epoxycadinane-4β,5β,10β,11-tetraol (2), bullatantiol-1β-methyl malate (3), 1β,4β,7α-trihydroxyeudesmane-1β-methyl malate (6), and 1β,4α,7-trihydroxyeudes-mane (7), together with five known sesquiterpenoids, bullatantriol (4), acetylbullatantriol (5), 1β,4β,7α-trihydroxyeudesmane (8), 1β,4β,7β-trihydroxyeude-smane (9), and pterodontriol (10). Their structures were elucidated on the basis of spectroscopic evidences, including various 1D and 2D NMR and HR-ESI-MS. The structure of 1 was further confirmed by single-crystal X-ray diffraction analysis.

Key words

Araceae - Homalomena occulta - sesquiterpenoids

Supporting Information

 

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