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Planta Med 2012; 78(09): 906-908
DOI: 10.1055/s-0031-1298537
DOI: 10.1055/s-0031-1298537
Biological and Pharmacological Activity
Letters
Leishmanicidal Compounds from the Fruits of Piper longum
Further Information
Publication History
received 01 March 2012
revised 12 April 2012
accepted 16 April 2012
Publication Date:
10 May 2012 (online)
Abstract
One new alkaloid amide, piperlongumide (1) [N-isobutyl-19-(3′,4′-methylenedioxyphenyl)-2E,4E nonadecadienamide], and six known compounds with leishmanicidal activity against promastigotes and axenic amastigotes of Leishmania donovani were isolated from the n-hexane fraction of the fruits of Piper longum. The structure of 1 was elucidated by spectroscopic evidences.
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References
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