Seresto® – ein neues Polymermatrix-Halsband mit den
					Wirkstoffen Flumethrin und Imidacloprid zum Langzeitschutz von Hunden und Katzen
					vor Floh- und Zeckenbefall

Literatur
1 Tarello W. Microscopic and clinical evidence for Anaplasma (Ehrlichia) phagocytophilum infection in Italian cats. Vet Rec 2005; 156: 772-774
2 Bjoersdorff A, Svendenius L, Owens JH et al. Feline granulocytic ehrlichiosis – a report of a new clinical entity and characterisation of the infectious agent. J Small Anim Pract 1999; 40: 20-24
3 Lappin MR, Breitschwerdt EB, Jensen WA et al. Molecular and serologic evidence of Anaplasma phagocytophilum infection in cats in North America. J Am Vet Med Assoc 2004; 225: 879-896
4 Solano-Gallego L, Hegarty B, Espada Y et al. Serological and molecular evidence of exposure to arthropod-borne organisms in cats from northeastern Spain. Vet Microbiol 2006; 118: 274-277
5 Buoro IB, Atwell RB, Kiptoon JC et al. Feline anaemia associated with Ehrlichia-like bodies in three domestic short-haired cats. Vet Rec 1989; 125: 434-436
6 Breitschwerdt EB, Abrams-Ogg AC, Lappin MR et al. Molecular evidence supporting Ehrlichia canis-like infection in cats. J Vet Intern Med 2002; 16: 642-649
7 Bouloy RP, Lappin MR, Holland CH et al. Clinical ehrlichiosis in a cat. J Am Vet Med Assoc 1994; 204: 1475-1478
8 Peavy GM, Holland CJ, Dutta SK et al. Suspected ehrlichial infection in five cats from a household. J Am Vet Med Assoc 1997; 210: 231-234
9 Bennett AD, Gunn-Moore DA, Brewer M et al. Prevalence of Bartonella species, haemoplasmas and Toxoplasma gondii in cats in Scotland. J Feline Med Surg 2011; 13: 553-557
10 Lappin MR, Hawley J. Presence of Bartonella species and Rickettsia species DNA in the blood, oral cavity, skin and claw beds of cats in the United States. Vet Dermatol 2009; 20: 509-514
11 Barrs VR, Beatty JA, Wilson BJ et al. Prevalence of Bartonella species, Rickettsia felis, haemoplasmas and the Ehrlichia group in the blood of cats and fleas in eastern Australia. Aust Vet J 2010; 88: 160-165
12 Kamrani A, Parreira VR, Greenwood J et al. The prevalence of Bartonella, hemoplasma, and Rickettsia felis infections in domestic cats and in cat fleas in Ontario. Can J Vet Res 2008; 72: 411-419
13 Juvet F, Lappin MR, Brennan S et al. Prevalence of selected infectious agents in cats in Ireland. J Feline Med Surg 2010; 12: 476-482
14 Tabar MD, Altet L, Francino O et al. Vector-borne infections in cats: molecular study in Barcelona area (Spain). Vet Parasitol 2008; 151: 332-336
15 Case JB, Chomel B, Nicholson W et al. Serological survey of vector-borne zoonotic pathogens in pet cats and cats from animal shelters and feral colonies. J Feline Med Surg 2006; 8: 111-117
16 Foley JE, Harrus S, Poland A et al. Molecular, clinical, and pathologic comparison of two distinct strains ofHaemobartonella felis in domestic cats. Am J Vet Res 1998; 59: 1581-1588
17 Foley JE, Pedersen NC. ‘Candidatus Mycoplasma haemominutum’, a low-virulence epierythrocytic parasite of cats. Int J Syst Evol Microbiol 2001; 51: 815-817
18 Neimark H, Johansson KE, Rikihisa Y et al. Proposal to transfer some members of the genera Haemobartonella andEperythrozoon to the genus Mycoplasma with descriptions of‘Candidatus Mycoplasma haemofelis’, ‘Candidatus Mycoplasma haemomuris’, ‘Candidatus Mycoplasma haemosuis’ and ‘CandidatusMycoplasma wenyonii’. Int J Syst Evol Microbiol 2001; 51: 891-899
19 Willi B, Boretti FS, Cattori V et al. Identification, molecular characterization, and experimental transmission of a new hemoplasma isolate from a cat with hemolytic anemia in Switzerland. J Clin Microbiol 2005; 43: 2581-2585
20 Bayliss DB, Morris AK, Horta M et al. Prevalence of Rickettsia species antibodies and Rickettsia species DNA in the blood of cats with and without fever. J Feline Med Surg 2009; 11: 266-270
21 Ortuño A, Castellà J, Criado-Fornelio A et al. Molecular detection of a Hepatozoon species in stray cats from a feline colony in North-eastern Spain. Vet J 2008; 177: 134-135
22 Baneth G, Aroch I, Tal N et al. Hepatozoon species infection in domestic cats: a retrospective study. Vet Parasitol 1998; 79: 123-33
23 Magnarelli LA, Bushmich SL, IJdo JW et al. Seroprevalence of antibodies against Borrelia burgdorferi andAnaplasma phagocytophilum in cats. Am J Vet Res 2005; 66: 1895-1899
24 Krupka I, Straubinger RK. Lyme borreliosis in dogs and cats: background, diagnosis, treatment and prevention of infections with Borrelia burgdorferi sensu stricto. Vet Clin North Am Small Anim Pract 2010; 40: 1103-1119
25 Ipsos. Current and future needs. Ectoparasiticides market research study. Bayer Internal Study Report 2011 on file
26 Skopos. European online ectoparasiticides market survey with 1500 pet owners. Bayer Internal Report 2011 on file
27 Stanneck D, Krieger KJ. Season long protection of dogs and cats against flea and tick infestations by a new slow release device for topical treatment containing imidacloprid and flumethrin. Poster Otto-Bayer Science Day 2010
28 Bundesamt für Verbraucherschutz und Lebensmittelsicherheit(BVL). Draft Publicly available Assessment Report for a Veterinary Medicinal Product: Seresto. 8. Nov. 2011, DE/V/143/001-004/DC
29 Arther RG, Cunningham J, Dorn H et al. Efficacy of imidacloprid for removal and control of fleas (Ctenocephalides felis) on dogs. Am J Vet Res 1997; 58: 848-850
30 Jacobs DE, Hutchinson MJ, Krieger KJ. Duration of activity of imidacloprid, a novel adulticide for flea control, against Ctenocephalides felis on cats. Vet Rec 1997; 140: 259-260
31 Turberg A. Flumethrin, imidacloprid in vitro comparative efficacy against Ixodes ricinus, Rhipicephalus sanguineus and Dermacentor reticulatuslarvae, nymphs and adults in a glass vial contact assay. Bayer Internal Study Report 2010; ID 33467
32 Löffler HU. Flea and tick collars for the prevention and control of ectoparasites in pets. Poster Otto-Bayer Science Day 2011
33 Boland LA, Angles JM. Feline permethrin toxicity: retrospective study of 42 cases. J Feline Med Surg 2010; 12: 61-71
34 Narahashi T. Nerve membrane Na channels as targets of insecticides. Trends Pharmacol Sci 1992; 13: 236-241
35 Vijverberg HP M, van den Berken J. Neurotoxicological effects and the mode of action of pyrethroid insecticides. Toxicol 1990; 21: 105-126
36 Ecobichon DJ. Toxic effects of pesticides. In: Klaassen CD, Amdur MO, Doull J, eds Casarett & Doull's Toxicology: The Basic Science of Poisons. New Xork: McGraw-Hill; 1996. 5. th edn. 643-689
37 Beasley VR, Dorman DC, Fikes FD et al. A Systems affected Approach to Veterinary Toxicology. Urbana: University of Illinois, College of Veterinary Medicine; 1997: 178-180
38 Saunders SD. Pesticides: Principles and Methods of Toxicology. Raven Press, New York 1994; 3 rd edn 389-415
39 Casida JE, Gammon DW, Glickman AH et al. Mechanisms of selective action of pyrethroid insecticides. Annu Rev Pharmacol 1983; 23: 413-438
40 Verschoyle RD, Aldridge WN. Structure-activity relationships of some pyrethroids in rats. Arch Toxicol 1980; 45: 325-329
41 Valentine WM, Beasley VR. Pyrethrins and Pyrethroids. In: Kirk RW. Current Veterinary Therapy X – Small Animal Practice. WB Saunders; 1989: 138
42 Soderlund DM, Clark JM, Sheets LP et al. Mechanisms of pyrethroid neurotoxicity: implications for cumulative risk assessment. Toxicol 2002; 171: 3-59
43 Liu MY, Casida JE. High affinity binding of [3H]imidacloprid in the insect acetylcholine receptor. Pestic Biochem Physiol 1993; 46: 40-46
44 Schoenhense E, Ebbinghaus-Kintscher U. A demonstration of in vitro synergism between imidacloprid and flumethrin at the level of an insect nerve cord preparation. Bayer Internal Study Report 2010; ID 36161
45 Turberg A. Comparative efficacy of flumethrin, imidacloprid and a 1:1.85 flumethrin:imidacloprid mixture against Ctenocephalides felis in-vitro in a glass vial contact assay. Bayer Internal Study Report 2010; ID 33465
46 Andrews P. Flumethrin and imidacloprid OECD study for acute oral combination toxicity in rats. Bayer Internal Study Report 2001; ID 25977
47 Kaneko H. Pyrethroid Chemistry and Metabolism. In: Krieger R, ed Handbook of Pesticide Toxicology Principles. London, San Diego: Academic Press; 2010
48 Bough M. Permethrin toxicosis in cats. Vet Tech 2000; Sept: 506-507
49 Meyer EK. Toxicosis in cats erroneously treated with 45 to 65% permethrin products. J Am Vet Med Assoc 1999; 5: 198-203
50 Reid FM, Oeheme FW. Toxicoses. In: Sherding RG, ed The Cat: Diseases and Clinical Management. New York: Churchill Livingstone; 1989: 190
51 Richardson JA. Permethrin spot-on toxicosis in cats. J Vet Emerg Crit Care 2000; 10: 103-106
52 Oehme FW. Clinical toxicology in small animals. In: Post-Graduate Committee in Veterinary Science: Proceedings no 103: Veterinary clinical toxicology. University of Sydney; August 24–28 1987: 443-476
53 Bomann W. Bayticol acid – Investigations of subacute toxicity in Wistar rats. Bayer Internal Study Report 1995; ID 24057, submitted to WHO
54 Cada A. Evaluation of target animal tolerance following oral administration of flumethrin to cats. Bayer Internal Study Report 2010; ID 33693
55 Hughes MF, Edwards BC. In vitro dermal absorption of pyrethroid pesticides in human and rat skin. Tox Appl Pharm 2010; 246: 29-37
56 Delport PC. Serum and hair coat kinetics of an Imidacloprid 10 %/flumethrin 4.5 % collar in cats. Bayer Internal Study Report 2010; ID 35642
57 Delport PC. Serum and hair coat kinetics of an imidacloprid 10 %/flumethrin 4.5 % collar in dogs. Bayer Internal Study Report 2010; ID 35643
58 Krebber R. Analytical method for the HPLC-MS/MS detection of imidacloprid and flumethrin in dog and cat serum. Bayer Internal Study Report 2010; ID 36234
59 Sjöberg P. Toxicological expert opinion on imidacloprid/flumethrin collar for cats and dogs. Bayer Internal Study Report 2010; ID 33189
60 Delport PC. Target animal safety studies with imidacloprid 10 %/flumethrin 4.5 % collars in dogs and cats. Bayer Internal Study Reports 2010; IDs 33692, 33697
61 Stanneck D. Applicants summary of preclinical and clinical trials with imidacloprid 10 %/flumethrin 4.5 % collar for cats and dogs. Bayer Internal Study Report 2010; ID 35997

Seresto® – ein neues Polymermatrix-Halsband mit den Wirkstoffen Flumethrin und Imidacloprid zum Langzeitschutz von Hunden und Katzen vor Floh- und Zeckenbefall

Seresto^® – ein neues Polymermatrix-Halsband mit den Wirkstoffen Flumethrin und Imidacloprid zum Langzeitschutz von Hunden und Katzen vor Floh- und Zeckenbefall