Grundlagen der Fototherapie

Lernziele

Kenntnisse im Bereich Fototherapie:

Grundlagen und Wirkmechanismen Indikationen Durchführung der einzelnen Fototherapiemodalitäten Unerwünschte Wirkungen der Fototherapie

Literatur

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• 2 Berneburg M, Lehmann A R. Xeroderma pigmentosum and related disorders: defects in DNA repair and transcription.  Adv Genet. 2001;  43 71-102
• 3 Kulms D, Schwarz T. Molecular mechanisms of UV-induced apoptosis.  Photodermatol Photoimmunol Photomed. 2000;  16 195-201
• 4 Schwarz T. The dark and the sunny sides of UVR-induced immunosuppression: photobiology revisited.  J Invest Dermatol. 2010;  130 49-51
• 5 Wlascheck M, Heinen G, Poswig A et al. UVA-induced autocrine stimulation of fibroblasts derived collagenase/MMP1 by interrelated loops of interleukin-1 and interleukin-6.  Photobiol. 1994;  59 550-556
• 6 Berneburg M, Gollnick E, Herzinger T et al. S1-Leitlinie Empfehlungen zur UV-Phototherapie und Photochemotherapie. Im Internet: http://www.awmf.org/uploads/tx_szleitlinien/013 – 029.pdf Stand: 1.12.2009
• 7 Storbeck H, Hölzle E, Schürer N et al. Narrow-band UVB (311 nm) versus conventional broad-band UVB with and without dithranol in phototherapy for psoriasis.  J Am Acad Dermatol. 1993;  28 227-231
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• 11 Njoo M D, Bos J D, Westerhof W. Treatment of generalized vitiligo in children with narrow-band (TL-01) UVB radiation.  J Am Acad Dermatol. 2000;  42 245-253
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• 13 Krutmann J, Schöpf E. High-dose UVA 1 phototherapy: a novel and highly effective approach for the treatment of acute exacerbation of atopic dermatitis.  Acta Derm Venereol Suppl (Stockh). 1992;  176 120-122
• 14 Kerscher M, Dirschka T, Volkenandt M. Treatment of localised scleroderma by UVA1 phototherapy.  Lancet. 1995;  346 1166
• 15 Kerscher M, Volkenandt M, Meurer M et al. PUVA-bath photochemotherapy of lichen planus.  Arch Dermatol. 1995;  131 1210-1211
• 16 Schwarz T, Rütter A, Hawk J. Phototherapy and photochemotherapy: less common indications for its use.. In: Krutmann J, Hönigsmann H, Elmets C A, Bergstresser P R, eds Dermatological phototherapy and photodiagnostic methods.. Berlin: Springer; 2001: 179-197
• 17 Radakovic S, Seeber A, Hönigsmann H et al. Failure of short-term psorelen and ultraviolet A light maintenance treatment to prevent early relapse in patients with chronic recurring plaque-type psoriasis.  Photodermatol Photoimmunol Photomed. 2009;  25 90-93
• 18 Stern R S, Lunder E J. Risk of squamous cell carcinoma and methoxsalen (psoralen) and UV-A radiation (PUVA). A meta-analysis.  Arch Dermatol. 1998;  134 1582-1585
• 19 Stern R S, Nichols K T, Vakeva L H. Malignant melanoma in patients treated for psoriasis with methoxsalen (psoralen) and ultraviolet A radiation (PUVA).  N Engl J Med. 1997;  336 1041-1045
• 20 Weischer M, Blum A, Eberhard F et al. No evidence for increased skin cancer risk in psoriasis patients treated with broadband or narrowband UVB phototherapy: a first retrospective study.  Acta Derm Venereol. 2004;  84 370-374
• 21 Hannuksela-Svahn A, Sigurgeirsson B, Pukkala E et al. Trioxsalen bath PUVA did not increase the risk of squamous cell skin carcinoma and cutaneous malignant melanoma in a joint analysis of 944 Swedish and Finnish patients with psoriasis.  Br J Dermatol. 1999;  141 497-501