Synthesis 2012(2): 194-200  
DOI: 10.1055/s-0031-1289597
PSP
© Georg Thieme Verlag Stuttgart ˙ New York

Convenient and Practical Synthesis of α-Amido Stannanes

Tsuyoshi Mita*, Yuki Higuchi, Yoshihiro Sato*
Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
Fax: +81(11)7064982; e-Mail: [email protected]; e-Mail: [email protected];
Further Information

Publication History

Received 6 October 2011
Publication Date:
09 November 2011 (online)

Abstract

Convenient and practical synthesis of N-Boc- and N-Cbz-α-amino stannanes from the corresponding α-amido sulfones was achieved. Yields of products are generally good to high because of the consequence of avoiding the isolation of unstable imine intermediates. The procedure is so simple that large-scale stannylation is possible without any difficulty.

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