Reduction of Nitro Compounds with N₂H₄˙H₂O Using Fe₃O₄ Nanoparticles

Significance

Commercially available Fe₃O₄ nanoparticles catalyzed the reduction of nitro compounds 1 with hydrazine hydrate to give the corresponding amines 2 in up to 99% yield (14 examples). The catalyst was recovered magnetically and reused nine times without loss of its catalytic activity for the formation of 2a (1^st reuse: 99% yield, 9^th reuse: 99% yield).