Klin Padiatr 2011; 223(06): 368-369
DOI: 10.1055/s-0031-1285880
Pictorial Essay
© Georg Thieme Verlag KG Stuttgart · New York

Acute Lymphoblastic Leukemia in a 10-Year-Old Boy With Cystic Fibrosis – Improvement of Pulmonary Function During Chemotherapy in spite of Intermittent Pseudomonas Aeruginosa Colonisation

Akute lymphoblastische Leukämie bei einem 10-jährigen Jungen mit zystischer Fibrose – Verbesserung der Lungenfunktion während Chemotherapie trotz intermittierender Pseudomonas-aeruginosa-Besiedlung
C. Dopfer
1  Department of Pediatrics, Cystic Fibrosis Centre, Jena University Hospital, Germany
,
K. Kentouche
2  Department of Pediatrics, Hematology and Oncology, Jena University Hospital, Germany
,
B. Gruhn
2  Department of Pediatrics, Hematology and Oncology, Jena University Hospital, Germany
,
R. Dopfer
3   Rehabilitation Hospital, Villingen-Schwenningen, Tannheim gGmbH, Germany
,
S. Becker
2  Department of Pediatrics, Hematology and Oncology, Jena University Hospital, Germany
,
H.-J. Mentzel
4  Pediatric Radiology, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Germany
,
J. F. Beck
2  Department of Pediatrics, Hematology and Oncology, Jena University Hospital, Germany
,
J. G. Mainz
1  Department of Pediatrics, Cystic Fibrosis Centre, Jena University Hospital, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
19 October 2011 (eFirst)

Background

Multiorgan involvement in cystic fibrosis (CF), including chronic airway infection with pathogens like Pseudomonas aeruginosa, is a critical risk factor in patients with malignancy during aggressive immunosuppressive therapy, and was therefore formerly associated with high mortality rates. A 10 year old boy with CF and acute lymphoblastic leukemia (ALL) underwent induction and reinduction treatment without severe infectious complications whereas lung function improved.