Planta Med 2011; 77 - PM155
DOI: 10.1055/s-0031-1282913

Antibacterial activity of the essential oil and main components of two Dracocephalum species from Iran

A Sonboli 1, A Gholipour 2, M Yousefzadi 3
  • 1Department of Biology, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran
  • 2Department of Biology, Payame Noor University (PNU), Sari, Mazandaran, Iran
  • 3Department of Marine Biology, Hormozgan University, Bandar Abbas, Iran

Antibacterial activity of Dracocephalum polychaetum Bornm. and D. surmandinum Rech.f. essential oils and two main components were investigated. Essential oils of the plants were analyzed by GC and GC-MS[1]. Twenty-three components were characterized in the essential oil of D. polychaetum. The oil was rich in oxygenated compounds (73.1%) and hydrocarbons (25.0%). Monoterpenes including perilla aldehyde (63.4%) and limonene (22.1%) were the major constituents. Among the 25 identified compounds (97.8%) in the oil of D. surmandinum perilla aldehyde (54.3%) and limonene (30.1%) were the main constituents. The bioassays exhibited that all of the Gram-positive and Gram-negative bacteria tested were highly inhibited in the presence of the oils and main components investigated. The most sensitive microorganism to the oils was found to be Staphylococcus epidermidis with the lowest MIC value of 0.3mg/ml. The resistant Gram-negative Pseudomonas aeruginosa was highly inhibited by the oil of D. polychaetum with MIC value of 2.4mg/ml.

Keywords: Dracocephalum, antibacterial activity, essential oil, perilla aldehyde, limonene

References: [1] Adams RP (2007) Identification of essential oils components by Gas Chromatography/Quadrupole Mass Spectroscopy. Allured Publishing. Carol Stream, IL.