Hepatoprotective action of the Egyptian variety of Phyllanthus atropurpureus

T Sarg; A El Sayed; R Zayed; M Al Sayed

doi:10.1055/s-0031-1282730

Planta Medica, Table of Contents

Hepatoprotective action of the Egyptian variety of Phyllanthus atropurpureus

T Sarg ¹, A El Sayed ¹, R Zayed ¹, M Al Sayed ¹

¹Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, 44519 Zagazig, Egypt

Abstract

Genus Phyllanthus (Family Euphorbiaceae) is considered as one of the important medicinal and ornamental plants. A phytochemical investigation of the extracts was performed to search for the active ingredient.

Results from the investigation of the hepatoprotective activity of Phyllanthus atropurpureus Bojer, revealed that its extracts is quite similar to silymarin. Both of them improve the parameters of CCl₄-induced liver injury including serum AST and ALT. Among the extracts tested, root extract showed maximum activity as compared with aerial part extract relative to silymarin.