Planta Med 2011; 77 - PG83
DOI: 10.1055/s-0031-1282567

Phytochemical study of Lagochilus cabulicus Benth

A Gohari 1, E Barari 2, S Saeidnia 1, A Shakeri 2, E Motaghedi 3
  • 1Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, PO Box 141556451, Tehran, Iran
  • 2Department of Chemistry, Faculty of cience, Golestan University, Gorgan, Iran
  • 3Department of Mechanical Engineering, Tabriz University, Tabriz, Iran

The genus, Lagochilus, belongs to Lamiaceae family and consists of 44 species all over the world, 33 of which grow in central Asia. Five species of this genus have been found in Flora Iranica and 4 species exclusively grow in Iran. Chemical studies on some Lagochilus species have studied [3–12]. One of these species, Lagochilus cabulicus Benth., was collected during flowering stage, dried at ambient temperature and shade condition and cut into small pieces. Plant material was successively extracted with ethyl acetate and methanol solvents using percolation method. Main compounds were separated and isolated by column and thin layer chromatography. The isolated compounds were identified by spectroscopic methods, including 1H-NMR and 13C-NMR.

In conclusion, four flavonoids, Tricetin 3'-methyl ether (1), Quercetin (2), Quercetin 3-O-β-D-glucopyranoside (3), Quercetin 3-O-α-L-rhamnopyranosyl (1®6) β-D-glucopyranoside (4), two steroids, β-Sitosteryl acetate (5), Stigmasteryl acetate (6) and one triterpenoid, Lupeol (7), have been identified, which not previously reported from this plant species.