Planta Med 2011; 77 - PG81
DOI: 10.1055/s-0031-1282565

Flavonol glycosides and a saponin from Chenopodium foliosum Asch

Z Kokanova Nedialkova 1, D Bücherl 2, S Nikolov 1, J Heilmann 2, P Nedialkov 1
  • 1Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria
  • 2Pharmaceutical Biology, Institute of Pharmacy, University of Regensburg, Regensburg, Germany

Three new flavonol glycosides and a new saponin, namely 6-methoxykaempferol-3-O-β-gentiobioside, gomphrenol-3-O-β-gentiobioside, gomphrenol-3-O-α-L-rhamnopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranoside and 3-O-β-D-glucopyranosyl-30-normedicagenic acid-28-β-D-glucopyranosyl ester as well as the known flavonol glycosides patuletin-3-O-β-gentiobioside and spinacetin-3-O-β-gentiobioside were isolated from the aerial parts of Chenopodium foliosum Asch. The structures of the compounds were established by means of spectroscopic methods (1D and 2D NMR, UV, IR, and HRMS). DPPH free radical scavenging activity and cytotoxicity (MTT-test) of the new compounds were assessed as well.

Acknowledgement: This study was supported by Medical Science Council at the Medical University of Sofia (Project 36/2011)