Planta Med 2011; 77 - PC8
DOI: 10.1055/s-0031-1282312

Antibacterial activity of some medicinal plants against antibiotics

M Jamshidi 1, E Gharaei Fathabad 2, M Eslamifar 3
  • 1Young Researchers Club, Islamic Azad University, Sari, Iran.
  • 2Department of Pharmacognosy and Biotechnology, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
  • 3Department of Environmental Health, faculty of Hygiene, Mazandaran University of Medical Sciences, Sari, Iran.

In this study, the antibacterial activity of 6 species of Lamiaceae family: Mentha spicata L., Mentha aquatica L., Stachys byzantina K.Koch, Marrubium vulgare L., Rosmarinus officinalis L. and Melissa officinalis L. were investigated.

The methanolic extracts of aerial parts of plants were evaluated in different concentrations according to the disk diffusion method by using Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Salmonella typhimurium, Streptococcus fecalis and Klebsiella pneumoniae and all the extracts were compared with standard antibiotic discs like vancomycin, ampicillin and chloramphenicol.

The methanolic extracts of Stachys byzantina and Rosmarinus officinalis were shown to inhibit, to different degrees, the growth of microorganisms (15–20mm). Furthermore, Stachys byzantina showed significant antimicrobial activity against Staphylococcus aureus resistant to vancomycin. The other plant extracts had shown lower antibacterial activity in comparison with standard antibiotics.

This study showed that some medicinal plants that were used in folk medicine significantly Stachys byzantina could be comparable with antibiotics and potential sources of new antimicrobial agents.