Planta Med 2011; 77 - PB38
DOI: 10.1055/s-0031-1282292

Study of endophytic fungi isolated from leaves of Hydnocarpus pentandra

PJ Hurakadle 1, AB Patil 2, HV Hegde 3
  • 1Pramod H J, Department of Pharmaceutical Biotechnology, KLE University College of Pharmacy, Nehrunagar, Belgaum-590 010, Karnataka, India
  • 2Abhijit B P, Department of Pharmaceutical Biotechnology, KLE University College of Pharmacy, Nehrunagar, Belgaum-590 010, Karnataka, India
  • 3Harsha V H, Regional Medical Research Centre, ICMR, Belgaum-590 010, Karnataka, India

Hydnocarpus pentandra Buch-Ham (Flacourtiaceae) an endangered species from Western Ghats region of India has been exploited traditionally against leprosy, rheumatic pain and inflammation. Ten endophytic fungi were isolated from the plant which are are a rich source of novel organic compounds with interesting biological

activities and a high level of biodiversity. They represent a relatively unexplored ecological source and their secondary metabolism is particularly active because of their metabolic interactions with their hosts.The APEF-12,13 (Dematicious sp., Fusarium sp.) showed maximum activity against bacteria B. subtilis and E.coli and APEF-06,15 (Cladosporium sp., non sporulating hyaline form) were most active against fungi C.albicans.

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