Planta Med 2010; 76 - P599
DOI: 10.1055/s-0030-1264897

Effect of parsley (Petroselinum crispum) extract on intra-abdominal fat deposition in mice

S Hosseini Biuki 1, M Anvari 2, M Dashti-R 2, F Zeinali Nasrabadi 3
  • 1Pharmacology Student, Pharmaceutical School, Isfahan Medical University Yazd, Iran, Islamic Republic Of
  • 2Assistant Professor, Shaheed Sadoughi Medical University Of Yazd Yazd, Iran, Islamic Republic Of
  • 3Medical Student, Shaheed Sadoughi Medical University Of Yazd Yazd, Iran, Islamic Republic Of

In this study the effects of non toxic concentrations of parsley (Petroselinum crispum) decoction (0.5%) on fat deposition in pregnant mice was assessed.

Methods: 40 adult female mice were mated overnight and checked daily for vaginal plaque until yielding 20 pregnant mice. The vaginal plaque observation was considered as the1st day of pregnancy. The remaining females were considered as non pregnant. Both pregnant and non pregnant animals were randomly and equally divided into 2 groups. Animals of both control groups received tap water while the animals in test groups received parsley decoction (0.5%) in the whole period of gestation ad libitum. 18 days after the onset of the experiments animals were sacrificed by deep anesthesia and striping fats deposited in the abdominal cavity from diaphragm to the genitalia were precisely removed and weighted.

Result: There was no significant difference between the fat deposition in pregnant and non pregnant animals and the intra abdominal fat deposition in all test groups.

Conclusion: In the literature it is reported that parsley decreases blood cholesterol in some patients1. However, our data indicate that parsley has not any effect on the intraabdominal fat deposition.

References: 1. Suido, H. et al. (2002)J Agric Food Chem. 50: 3346–50.