Planta Med 2010; 76 - P324
DOI: 10.1055/s-0030-1264622

A new flavonoidal compound from Diospyros lotus L. leaves

A Said 1, U Hawas 1, K Rashed 1, A Hüfner 2
  • 1National Research Centre, Pharmacognosy, El-Bohoss Str., Dokki, Giza, 111231 Cairo, Egypt
  • 2Graz University, Pharmaceutical Chemistry, Austria, 111123 Austria, Austria

In our complementary study of the chemical constituents from aqueous-methanolic extract of Diospyros lotus L. leaves, in addition to seven flavonoid compounds (myricetin 3-O-β-glucoside, quercetin 3-O-α-rhamnoside, quercetin 3-O-β-glucoside, quercetin 3-O-β-galactoside, rutin, quercetin 3-O-β-glucuronoide, kaempferol 3-O-α-rhamnoside), a new natural product quercetin 3-O-β-glucuronide-3′-O-[6′′′-O-galloyl)-5″-O-galloyl]-O-β-D-glucoside was isolated for the first time. The aqueous-methanolic extract of D. lotus leaves and some isolated compounds proved a significant antioxidative effect and antitumor activities[1] as well as a significant hepatoprotective effect [2].

References: 1. Monica Rosa Loizzo, Ataa Said, Rosa Tundis, Usama W. Hawas, Khaled Rashed, Francseco Mechichini. Antioxidant and Antiproliferative Activity of Diospyros lotus L. Extract and Isolated Compounds. Plant Foods Human Nutrition Journal 2009, 64, 264–270.

2. A. Said, Usama W. Hawas, Salwa M. Nofal, K. Rashed and Antje Huefner. Pharmaco-Chemical Studies on the Aqueous Methanolic Extract of Diospyros lotus Leaves. Research Journal of Phytochemistry 2009, 3(1), 1–12.