Planta Med 2010; 76 - P306
DOI: 10.1055/s-0030-1264604

The use of bark from Stryphonodendron barbatiman martius tree in cutaneous wounds

B Lopes 1, P Galera 1, M Rocha 1, A Silva 1, M Castro 1, RF Melo 2
  • 1Universidade de Brasília, Veterinary Medicine, Campus Universitário Darci Ribeiro, Asa Norte, 70000 Brasília, Brazil
  • 2UPIS – Brasília, Veterinary Medicine, Fazenda Lagoa Bonita, Planaltina, 70000 Brasília, Brazil

Several herbal compounds have been used in different cutaneous wounds aiming to decrease the time of cicatrization. The use of bark from S. barbatiman tree represents a very common kind of treatment of wounds in animals and human in Brazil. In this work, the application of S. barbatiman bark extract was carried to analyze the cicatrization process of cutaneous wounds of 2cm, which were produced surgically on dorse of 20 mice. In the first group, 15 animals were treated using ointment formulation containing 10% of ethanol extracts of S. barbatiman. In the control group, 5 animals do not received treatment. The wounds were measured to each 7 days until the 21th day. The treatment showed to be effective, and on 21th day the wounds were completely cicatrized, whereas the animals that not received any treatment presented discrete decrease of wound size at the same time. Histological analysis from tissues obtained from animals that received treatment showed the epithelial tissue formation from 10th day. On the other hand, only from 18th day, little epithelial tissue formation was observed in the control group, without total cicatrization on the 21th day. This data suggest that the use of bark from S. barbatiman tree could represent an efficient and rapid method of wound treatment.