Planta Med 2010; 76 - P204
DOI: 10.1055/s-0030-1264502

Furanocoumarins from root of Peucedanum ruthenicum (Apiaceae)

N Yassa 1, HRS Alavi 1
  • 1Faculty of Pharmacy, Tehran University of Medical Sciences, Pharmacognosy, Enghelab Avenue, 1414714411 Tehran, Iran, Islamic Republic Of

Peucedanum ruthenicum M. Bieb. (Apiaceae) is one of the Peucedanum complexes. This complex has some problem in systematic classification. P. ruthenicum aerial parts and root were collected from Mazandaran Provinces in the north of Iran on October and deposited with (Salimian 39) Voucher No. at private herbarium of Dr. Hossain Akhani in Dept. of Plant Sciences, Faculty of Sciencses, University of Tehran, Tehran, Iran. For possibility of its comparison to other genus and species in Pencedanum complex, different compounds from P. ruthenicum extract were isolated with chromatographic methods. Coumarins, phenolic acids, terpenoids, flavonoids, fatty acids, normal alkans and one carbohydrate were isolated and identified and identified with different spectroscopic methods such as NMR, Mass, UV and IR. But the coumarins which isolated and purified from root extract were reported. They are included: peucedanin 1, oxypeucedanin hydrate 2, xanthotoxin 3, psoralen 4, isopimpinellin 5, bergapten 6, 7-methoxy coumarin 7 and three new coumarins as 12-methoxy furanocoumarin 8; 5-prenyl, 12-methoxy furanocoumarin 9 and 5-prenyl furanocoumarin, 12 (3, 3-dimethyl) acrylate 10.