Planta Med 2010; 76 - P197
DOI: 10.1055/s-0030-1264495

New alkylresorcinols from the bulbs of Urginea indica L. collected in Nigeria

H Mikail 1, P Magiatis 1, A Skaltsounis 1
  • 1University of Athens, Faculty of Pharmacy, Department of Pharmacognosy and Natural Products Chemistry, Panepistimiopolis Zografou, 15771 Athens, Greece

Alkylresorcinols constitute a category of lipophilic polyphenols found in specific plant families. In this work, several alkylresorcinols presenting the substitution pattern of structures 1 and 2, were isolated from the dichloromethane extract of the air-dried bulbs of Urginea indica L. (Liliaceae) collected in Nigeria. Compounds of structure 1 with n=17, 19 and 21 as well as compounds of structure 2 with n=12, 14 and 17 are new. In addition, several other known compounds were identified: polyunsaturated fatty acids and squalene. The structures of the new compounds were elucidated on the basis of their NMR and MS data. The exact number of homologues in each series 1 and 2 and the exact length of the side chain was found using GC-MS analysis. The new compounds of structure 2 are lower homologues of cichoriols previously reported in Cichorium spinosum [1].

Fig.1: New alkyresorcinols

References: 1. Melliou, E. et al. (2003)J. Agric. Food Chem. 128:1620–1625.