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Isolation and biological evaluation of a triterpenoid from fruits of wild caraway (Bunium persicum Boiss.)
Bunium persicum Boiss. is an Apiaceaous plant endemic to Iran plateau, and its fruits are used as spice because of their carminative, antispasmodic properties and to promote formation of milk in lactating women . Anti-inflammatory , anti-oxidant , fungicide  and anti-histaminic  effect of the plant have been reported before, as well as studies on its volatile oil, that is rich in cyclic monoterpene aldehydes . Surprising, few investigations have been carried out on the non-volatile constituents of this plant. We now report the isolation and bioactivity of the monoacetate of a pentacyclic triterpene diol (1) from this plant which showed moderately activity in the croton oil dermatitis assay representing a novel dietary phytochemical worth further biological investigation because of its broad consumption.
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