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New jatrophanes from Euphorbia bungei Boiss.
Spurges (Euphorbia species) have an important role in the Iranian traditional medicine as wart removers as well as anti-asthmatic- and anti-arthritic agents , and many of them are endemic. This, and the exuberant chemical profligacy of spurges in terms of the production of secondary metabolites, has provided a rationale to investigate the phytochemistry of E. bungei Boiss. This species contains a high concentration of fats and free fatty acid, but a diterpenoid fraction was eventually obtained by the combined use of liquid/liquid and solid/liquid partitions and lead acetate depigmentation. The major constituents of this fraction turned out to be jatrophane derivatives, as exemplified by the novel polyesters 1 and 2, whose structures were elucidated by modern spectroscopic techniques.
References: 1. Zargari, A. (1993). Medicinal Plants, 5th ed., vol. 4. Tehran University Publication, Tehran.