Planta Med 2010; 76 - P169
DOI: 10.1055/s-0030-1264467

New jatrophanes from Euphorbia bungei Boiss.

Y Shokoohinia 1, O Taglialatela-Scafati 2, S Sajjadi 1, B Zolfaghari 1, G Appendino 3
  • 1Department of Pharmacognosy, Faculty of Pharmacy, Isfahan University of Medical Sciences, Hezar jarib Ave Isfahan, Iran, Islamic Republic Of
  • 2Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli Federico II, Via Montesano 49, 80131 Napoli, Italy
  • 3Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy

Spurges (Euphorbia species) have an important role in the Iranian traditional medicine as wart removers as well as anti-asthmatic- and anti-arthritic agents [1], and many of them are endemic. This, and the exuberant chemical profligacy of spurges in terms of the production of secondary metabolites, has provided a rationale to investigate the phytochemistry of E. bungei Boiss. This species contains a high concentration of fats and free fatty acid, but a diterpenoid fraction was eventually obtained by the combined use of liquid/liquid and solid/liquid partitions and lead acetate depigmentation. The major constituents of this fraction turned out to be jatrophane derivatives, as exemplified by the novel polyesters 1 and 2, whose structures were elucidated by modern spectroscopic techniques.


References: 1. Zargari, A. (1993). Medicinal Plants, 5th ed., vol. 4. Tehran University Publication, Tehran.