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DOI: 10.1055/s-0030-1264348
Triterpenoidal saponins from Hydrocotyle bonariensis
The genus Hydrocotyle is an aquatic or semi-aquatic plant having antioxidant and antitumoral activity [1, 2]. Earlier investigations have reported on a therapeutic action on ulcer, wounds, eczemas, and antitumour activity of compounds from Hydrocotyle species [3, 4]. This genus is particularly well represented in temperate areas and higher tropical region [5]. There are very rich in saponins, which have many interesting biological activities such as anti-inflamatory, antimicrobial, molluscicidal, cytotoxic, and antitumor properties [6]. In view of the biological and pharmacological importance of this type of secondary metabolites, we have focused our intention in the study of H. bonariensis. It is a hairless and creepy perennial plant. In the present research, we describe the isolation and structure elucidation of six new oleanane-type triterpenoidal saponins, Bonarienosides A-F (1 - 6) from the 70% aqueous MeOH extract of Hydrocotyle bonariensis roots. Their structures were established on the basis of NMR spectroscopic data (13C, 1H, COSY, HMBC, TOCSY, and NOESY) and mass spectrometry.
Acknowledgements: The authors are grateful to the Conseil Régional de Bourgogne, France for financial support.
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