© Georg Thieme Verlag KG Stuttgart · New York
Outcome of Congenital Diaphragmatic Hernia Repair Depending on Patch Type
received March 12, 2010
accepted after revision May 15, 2010
15. Oktober 2010 (online)
Introduction: Patch repair of a congenital diaphragmatic hernia is associated with a much higher rate of recurrence than when primary repair is feasible. The biosynthetic options for the repair materials continue to expand. We therefore reviewed our experience to benchmark complication rates as we progress with the use of new materials.
Methods: A retrospective review was conducted of all patients who underwent repair of congenital diaphragmatic hernia from January 1994 to May 2009.
Results: Of the 155 patients included in the study, 101 patients had primary closure and 54 received a diaphragmatic patch. The rates of recurrence, Small Bowel Obstruction (SBO), and subsequent abdominal operation were all significantly higher in the group of patients requiring patch repair. There were 3 types of patch repairs: 37 patients received a SIS patch, 12 had a nonabsorbable patch, and 5 received an AlloDerm patch. The incidence of SBO in patients with a nonabsorbable mesh was 17% and was associated with a 50% recurrence rate and 67% re-recurrence rate. SIS was associated with 19% incidence of SBO, a recurrence rate of 22% and a 50% re-recurrence rate, whereas AlloDerm had a 40% incidence of SBO, 40% recurrence rate, and 100% re-recurrence rate.
Discussion: As we move towards the next generation of materials, these data do not justify the continued comparison with nonabsorbable patches. We do not have enough comparative data to define a superior biosynthetic material, but we plan to use our data on SIS to benchmark our experience with future generation materials.
congenital diaphragmatic hernia - patch - recurrence - obstruction
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Dr. Shawn David St. Peter
Children's Mercy Hospital
Department of Surgery
Center for Prospective Trials
2401 Gillham Road MO
64108 Kansas City
Telefon: +1/816/983 3575
Fax: +1/816/983 6885