Kardiologie up2date 2011; 7(3): 170-172
DOI: 10.1055/s-0030-1256620
Hotline – Thrombozyten und Gerinnungssystem bei kardiovaskulären Erkrankungen

© Georg Thieme Verlag KG Stuttgart · New York

Perioperatives Management der antithrombotischen Behandlung bei Stent-Patienten

Boris  Bigalke
Further Information

Publication History

Publication Date:
25 October 2011 (online)


Perioperative management of antiplatelet treatment in patients with coronary stents remains challenging as premature discontinuation may cause thrombotic events. To date, there is a lack of evidence-based results and guidelines to recommend adequate antithrombotic drug therapy in patients at high risk of stent thrombosis who undergo noncardiac surgery. According to our clinical experience with these patients, we propose a perioperative bridging of discontinued dual antiplatelet therapy by the „off-label“ use of low molecular weight glycoprotein IIbIIIa antagonist for up to 24 hours. Patients should be monitored by a perioperative point-of-care-testing and, thus, could benefit from the individually adapted antiplatelet therapeutic issue.


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Priv.-Doz. Dr. med. Boris Bigalke

Medizinische Klinik III
Eberhard-Karls-Universität Tübingen

72076 Tübingen

Email: [email protected]