Kardiologie up2date 2011; 7(2): 97-101
DOI: 10.1055/s-0030-1256517
Hotline – Aortenerkrankungen

© Georg Thieme Verlag KG Stuttgart · New York

Renale Denervierung bei therapierefraktärer Hypertonie

Britta  Weidtmann, Mark  Rosenberg, Hendrik  Bonnemeier, Norbert  Frey
Further Information

Publication History

Publication Date:
21 July 2011 (online)

Abstract

Overactivity of the sympathetic nervous system has been identified as an important contributor to resistant hypertension. Renal artery radiofrequency ablation is a new therapeutic approach for these patients. As shown in the Simplicity HTN-1 and -2 trials, there is evidence that catheter-based renal denervation has a substantial impact on central sympathetic outflow by reducing the renal norephedrine spillover and is associated with a sustained reduction in blood pressure. Importantly, these studies demonstrated peri- and postinterventional safety and may thus represent a promising option in management of patients with therapy-resistant hypertension as well as concomitant comorbidities.

Literatur

Prof. Dr. Norbert Frey

Klinik für Kardiologie und Angiologie
Universitätsklinikum Schleswig-Holstein, Campus Kiel

Arnold-Heller Str. 3 (Haus 6)
24105 Kiel

Email: [email protected]

Dr. med. Mark Rosenberg

Klinik für Kardiologie und Angiologie
Universitätsklinikum Schleswig-Holstein, Campus Kiel

Arnold-Heller Str. 3 (Haus 6)
24105 Kiel

Email: [email protected]

Prof. Dr. Hendrik Bonnemeier

Klinik für Kardiologie und Angiologie
Universitätsklinikum Schleswig-Holstein, Campus Kiel

Arnold-Heller Str. 3 (Haus 6)
24105 Kiel

Email: [email protected]

Dr. med. Britta Weidtmann

Klinik für Kardiologie und Angiologie
Universitätsklinikum Schleswig-Holstein, Campus Kiel

Arnold-Heller Str. 3 (Haus 6)
24105 Kiel

Email: [email protected]