Der Nuklearmediziner 2010; 33(2): 91-104
DOI: 10.1055/s-0030-1252000
Myokardszintigrafie – 2010

© Georg Thieme Verlag KG Stuttgart · New York

Quantifizierung der Perfusion und Risikostratifizierung durch die Myokardperfusions-SPECT

Quantification of Perfusion and Risk Stratification by Myocardial Perfusion SPECTB. Nowak1 , 2 , W. M. Schäfer3
  • 1Überörtliche Gemeinschaft (GbR) für diagnostische und interventionelle Radiologie und Nuklearmedizin (DIRANUK), Bielefeld
  • 2Klinik für Nuklearmedizin, Klinikum Bielefeld-Mitte
  • 3Klinik für Nuklearmedizin, Kliniken Maria Hilf GmbH, Krankenhaus St. Franziskus, Mönchengladbach
Further Information

Publication History

Publication Date:
31 May 2010 (online)

Zusammenfassung

Die Myokardperfusions-SPECT diagnostiziert eine hämodynamisch relevante koronare Herzerkrankung mit hoher Sensitivität und Spezifität, gestattet eine semiquantitative Erfassung des Schweregrades und der Ausdehnung einer Myokardischämie und ermöglicht darüber hinaus eine zuverlässige Abschätzung der zukünftigen kardialen Ereignisrate unabhängig von anderen klinischen und diagnostischen Parametern. Ein Normalbefund in der Myokardperfusions-SPECT weist auf eine günstige Prognose hin und rechtfertigt eine restriktive Vorgehensweise. Mit zunehmendem Ausmaß von Perfusionsstörungen steigt das kardiale Risiko an. Eine differenzierte Betrachtung quantitativer Parameter der Myokardperfusions-SPECT erlaubt eine effektive Risikostratifizierung von Patienten unterschiedlichster Risikokonstellationen.

Abstract

Myocardial perfusion SPECT detects flow-limiting coronary artery disease with high sensitivity and specificity, enables semiquantification of severity and extensiveness of myocardial ischemia, and furthermore enables reliable assessment of future cardiac events independently of other clinical and diagnostic parameters. A normal myocardial perfusion SPECT is associated with a favorable prognosis and warrants restrictive patient management. Cardiac risk increases in relation to the severity of perfusion abnormalities. Differentiated analysis of quantitative parameters derived from myocardial perfusion SPECT provides effective risk stratification of patients with a large variety of risk factors.

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PD Dr. Bernd Nowak

Überörtliche Gemeinschaft

(GbR) für diagnostische und

interventionelle Radiologie und

Nuklearmedizin (DIRANUK)

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