Whole-Body Magnetic Resonance Imaging in Skeletal Muscle Disease

Martin J Shelly; Ferdia Bolster; Paul Foran; Ian Crosbie; Eoin C Kavanagh; Stephen J Eustace

doi:10.1055/s-0030-1248704

Seminars in Musculoskeletal Radiology, Table of Contents

Semin Musculoskelet Radiol 2010; 14(1): 047-056
DOI: 10.1055/s-0030-1248704

Whole-Body Magnetic Resonance Imaging in Skeletal Muscle Disease

Martin J. Shelly¹ , Ferdia Bolster¹ , Paul Foran¹ , Ian Crosbie¹ , Eoin C. Kavanagh¹ ^, ² , Stephen J. Eustace¹ ^, ² ^, ³

¹Department of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland
²Department of Radiology, Cappagh National Orthopaedic Hospital, Finglas, Dublin, Ireland
³Department of Radiology, University College Dublin, Dublin, Ireland

Abstract

ABSTRACT

The evaluation of muscle diseases has traditionally integrated clinical with biochemical findings, occasionally resorting to muscle biopsy. This article reviews the role and imaging appearances of muscle diseases at MRI, specifically emphasising the role of WBMRI in global assessment of muscle abnormality, and in particular its role in determining distribution and extent of muscle abnormality.

KEYWORDS

Whole-body MRI - inflammatory myopathy - neuromuscular disorders - muscle atrophy - muscle edema

Full Text

References

REFERENCES

1 Farber J M, Buckwalter K A. MR imaging in nonneoplastic muscle disorders of the lower extremity. Radiol Clin North Am. 2002; 40(5) 1013-1031
2 Ahn J M, El-Khoury G Y. Role of magnetic resonance imaging in musculoskeletal trauma. Top Magn Reson Imaging. 2007; 18(3) 155-168
3 Schmidt G P, Reiser M F, Baur-Melnyk A. Whole-body imaging of the musculoskeletal system: the value of MR imaging. Skeletal Radiol. 2007; 36(12) 1109-1119
4 Chan W P, Liu G C. MR imaging of primary skeletal muscle diseases in children. AJR Am J Roentgenol. 2002; 179(4) 989-997
5 Napier N, Shortt C, Eustace S. Muscle edema: classification, mechanisms, and interpretation. Semin Musculoskelet Radiol. 2006; 10(4) 258-267
6 Rybak L D, Torriani M. Magnetic resonance imaging of sports-related muscle injuries. Top Magn Reson Imaging. 2003; 14(2) 209-219
7 May D A, Disler D G, Jones E A, Balkissoon A A, Manaster B J. Abnormal signal intensity in skeletal muscle at MR imaging: patterns, pearls, and pitfalls. Radiographics. 2000; 20(Spec No) S295-S315
8 Snell R S. Introduction. In: Clinical Anatomy for Medical Students. 5th ed. Boston, MA; Little, Brown 1995: 1-45
9 Adams E M, Chow C K, Premkumar A, Plotz P H. The idiopathic inflammatory myopathies: spectrum of MR imaging findings. Radiographics. 1995; 15(3) 563-574
10 Dahnert W. Radiology Review Manual. 6th ed. Philadelphia, PA; Lippincott Williams & Wilkins 2007
11 Curiel R V, Jones R, Brindle K. Magnetic resonance imaging of the idiopathic inflammatory myopathies: structural and clinical aspects. Ann N Y Acad Sci. 2009; 1154 101-114
12 Weckbach S. Whole-body MR imaging for patients with rheumatism. Eur J Radiol. 2009; 70(3) 431-441
13 Hargaden G, O'Connell M, Kavanagh E, Powell T, Ward R, Eustace S. Current concepts in whole-body imaging using turbo short tau inversion recovery MR imaging. AJR Am J Roentgenol. 2003; 180(1) 247-252
14 O'Connell M J, Powell T, Brennan D, Lynch T, McCarthy C J, Eustace S J. Whole-body MR imaging in the diagnosis of polymyositis. AJR Am J Roentgenol. 2002; 179(4) 967-971
15 Dalakas M C, Hohlfeld R. Polymyositis and dermatomyositis. Lancet. 2003; 362(9388) 971-982
16 Wong E H, Hui A C, Griffith J F, Wong S M, Szeto C C. MRI in biopsy-negative dermatomyositis. Neurology. 2005; 64(4) 750
17 Connor A, Stebbings S, Anne Hung N, Hammond-Tooke G, Meikle G, Highton J. STIR MRI to direct muscle biopsy in suspected idiopathic inflammatory myopathy. J Clin Rheumatol. 2007; 13(6) 341-345
18 Tomasová Studynková J, Charvát F, Jarosová K, Vencovsky J. The role of MRI in the assessment of polymyositis and dermatomyositis. Rheumatology (Oxford). 2007; 46(7) 1174-1179
19 Schweitzer M E, Fort J. Cost-effectiveness of MR imaging in evaluating polymyositis. AJR Am J Roentgenol. 1995; 165(6) 1469-1471
20 Lundberg I E, Alexanderson H. Technology insight: tools for research, diagnosis and clinical assessment of treatment in idiopathic inflammatory myopathies. Nat Clin Pract Rheumatol. 2007; 3(5) 282-290
21 Olsen N J, Qi J, Park J H. Imaging and skeletal muscle disease. Curr Rheumatol Rep. 2005; 7(2) 106-114
22 Tzaribachev N, Well C, Schedel J, Horger M. Whole-body MRI: a helpful diagnostic tool for juvenile dermatomyositis case report and review of the literature. Rheumatol Int. 2009; 29(12) 1511-1514
23 Lovitt S, Moore S L, Marden F A. The use of MRI in the evaluation of myopathy. Clin Neurophysiol. 2006; 117(3) 486-495
24 Walker U A. Imaging tools for the clinical assessment of idiopathic inflammatory myositis. Curr Opin Rheumatol. 2008; 20(6) 656-661
25 Maillard S M, Jones R, Owens C et al.. Quantitative assessment of MRI T2 relaxation time of thigh muscles in juvenile dermatomyositis. Rheumatology (Oxford). 2004; 43(5) 603-608
26 Kumar V AA, Fausto N, Aster J. Acute and chronic inflammation. In: Kumar VAA, Fausto N, Aster J Robbins and Cotran Pathologic Basis of Disease. 8th ed. Philadelphia, PA; Saunders 2010: 43-77
27 Dalakas M C. Mechanisms of disease: signaling pathways and immunobiology of inflammatory myopathies. Nat Clin Pract Rheumatol. 2006; 2(4) 219-227
28 Bohan A, Peter J B. Polymyositis and dermatomyositis (first of two parts). N Engl J Med. 1975; 292(7) 344-347
29 Bohan A, Peter J B. Polymyositis and dermatomyositis (second of two parts). N Engl J Med. 1975; 292(8) 403-407
30 Fleckenstein J L, Reimers C D. Inflammatory myopathies: radiologic evaluation. Radiol Clin North Am. 1996; 34(2) 427-439, xii
31 Anthony D CFM, De Girolami U. Peripheral nerve and skeletal muscle. In: Kumar VAA, Fausto N, Aster J Robbins and Cotran Pathologic Basis of Disease. 8th ed. Philadelphia, PA; Saunders 2010: 1257-1277
32 Cantwell C, Ryan M, O'Connell M et al.. A comparison of inflammatory myopathies at whole-body turbo STIR MRI. Clin Radiol. 2005; 60(2) 261-267
33 Askanas V, Engel W K. Inclusion-body myositis, a multifactorial muscle disease associated with aging: current concepts of pathogenesis. Curr Opin Rheumatol. 2007; 19(6) 550-559
34 Palmer W E, Kuong S J, Elmadbouh H M. MR imaging of myotendinous strain. AJR Am J Roentgenol. 1999; 173(3) 703-709
35 De Smet A A. Magnetic resonance findings in skeletal muscle tears. Skeletal Radiol. 1993; 22(7) 479-484
36 Helms C A, Martinez S, Speer K P. Acute brachial neuritis (Parsonage-Turner syndrome): MR imaging appearance—report of three cases. Radiology. 1998; 207(1) 255-259
37 Kamath S, Venkatanarasimha N, Walsh M A, Hughes P M. MRI appearance of muscle denervation. Skeletal Radiol. 2008; 37(5) 397-404
38 Misamore G W, Lehman D E. Parsonage-Turner syndrome (acute brachial neuritis). J Bone Joint Surg Am. 1996; 78(9) 1405-1408
39 Kikuchi Y, Nakamura T, Takayama S, Horiuchi Y, Toyama Y. MR imaging in the diagnosis of denervated and reinnervated skeletal muscles: experimental study in rats. Radiology. 2003; 229(3) 861-867
40 Ryan M, Twair A, Nelson E, Brennan D, Eustace S. Whole body magnetic resonance imaging in the diagnosis of Parsonage Turner syndrome. Acta Radiol. 2004; 45(5) 534-539
41 Beltran J, Simon D C, Katz W, Weis L D. Increased MR signal intensity in skeletal muscle adjacent to malignant tumors: pathologic correlation and clinical relevance. Radiology. 1987; 162(1 Pt 1) 251-255
42 May D A, Good R B, Smith D K, Parsons T W. MR imaging of musculoskeletal tumors and tumor mimickers with intravenous gadolinium: experience with 242 patients. Skeletal Radiol. 1997; 26(1) 2-15
43 Weatherall P. Imaging of muscle tumors. Semin Musculoskelet Radiol. 2000; 4(4) 435-458
44 Rosenberg A. Bones, joints, and soft tissue tumors. In: Cotran RS, Robbins SL, Collins T, Kumar V Robbins Pathologic Basis of Disease. 6th ed. Philadelphia, PA; Saunders 1999: 1259-1267
45 Stein-Wexler R. MR imaging of soft tissue masses in children. Magn Reson Imaging Clin N Am. 2009; 17(3) 489-507
46 Shelly M J, MacMahon P J, Eustace S. Radiology of soft tissue tumors including melanoma. Cancer Treat Res. 2008; 143 423-452
47 Pappo A S, Shapiro D N, Crist W M. Rhabdomyosarcoma. Biology and treatment. Pediatr Clin North Am. 1997; 44(4) 953-972
48 Yousem D M, Lexa F J, Bilaniuk L T, Zimmerman R I. Rhabdomyosarcomas in the head and neck: MR imaging evaluation. Radiology. 1990; 177(3) 683-686
49 Fleckenstein J L, Watumull D, Conner K E et al.. Denervated human skeletal muscle: MR imaging evaluation. Radiology. 1993; 187(1) 213-218
50 Ozsarlak O, Parizel P M, De Schepper A M, De Jonghe P, Martin J J. Whole-body MR screening of muscles in the evaluation of neuromuscular diseases. Eur Radiol. 2004; 14(8) 1489-1493
51 Mercuri E, Pichiecchio A, Allsop J, Messina S, Pane M, Muntoni F. Muscle MRI in inherited neuromuscular disorders: past, present, and future. J Magn Reson Imaging. 2007; 25(2) 433-440
52 Liu G C, Jong Y J, Chiang C H, Jaw T S. Duchenne muscular dystrophy: MR grading system with functional correlation. Radiology. 1993; 186(2) 475-480
53 Messineo D, Cremona A, Trinci M, Francia A, Marini A. MRI in the study of distal primary myopathies and of muscular alterations due to peripheral neuropathies: possible diagnostic capacities of MR equipment with low intensity field (0.2 T) dedicated to peripheral limbs. Magn Reson Imaging. 1998; 16(7) 731-741
54 Lamminen A E. Magnetic resonance imaging of primary skeletal muscle diseases: patterns of distribution and severity of involvement. Br J Radiol. 1990; 63(756) 946-950
55 Ozsarlak O, Schepens E, Parizel P M et al.. Hereditary neuromuscular diseases. Eur J Radiol. 2001; 40(3) 184-197
56 Pichiecchio A, Uggetti C, Egitto M G et al.. Quantitative MR evaluation of body composition in patients with Duchenne muscular dystrophy. Eur Radiol. 2002; 12(11) 2704-2709
57 Manzur A Y, Muntoni F. Diagnosis and new treatments in muscular dystrophies. J Neurol Neurosurg Psychiatry. 2009; 80(7) 706-714
58 Schreiber A, Smith W L, Ionasescu V et al.. Magnetic resonance imaging of children with Duchenne muscular dystrophy. Pediatr Radiol. 1987; 17(6) 495-497
59 Schara U, Schoser B G. Myotonic dystrophies type 1 and 2: a summary on current aspects. Semin Pediatr Neurol. 2006; 13(2) 71-79
60 Day J W, Ricker K, Jacobsen J F et al.. Myotonic dystrophy type 2: molecular, diagnostic and clinical spectrum. Neurology. 2003; 60(4) 657-664
61 Wheeler T M, Thornton C A. Myotonic dystrophy: RNA-mediated muscle disease. Curr Opin Neurol. 2007; 20(5) 572-576
62 Kornblum C, Lutterbey G, Bogdanow M et al.. Distinct neuromuscular phenotypes in myotonic dystrophy types 1 and 2: a whole body highfield MRI study. J Neurol. 2006; 253(6) 753-761
63 Damian M S, Bachmann G, Herrmann D, Dorndorf W. Magnetic resonance imaging of muscle and brain in myotonic dystrophy. J Neurol. 1993; 240(1) 8-12
64 Castillo J, Pumar J M, Rodríguez J R et al.. Magnetic resonance imaging of muscles in myotonic dystrophy. Eur J Radiol. 1993; 17(3) 141-144
65 Fleckenstein J L. MRI of neuromuscular disease: the basics. Semin Musculoskelet Radiol. 2000; 4(4) 393-419
66 Brennan D D, Whelan P F, Robinson K et al.. Rapid automated measurement of body fat distribution from whole-body MRI. AJR Am J Roentgenol. 2005; 185(2) 418-423

Martin J ShellyM.D.

Department of Radiology, Mater Misericordiae University Hospital

Eccles St., Dublin 7, Ireland

Email: martinshelly@gmail.com