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Z Gastroenterol 2010; 48(12): 1384-1404
DOI: 10.1055/s-0029-1245788
Positionspapier

© Georg Thieme Verlag KG Stuttgart · New York

Kapselendoskopie in der Diagnostik von Dünndarmerkrankungen

Update des Positionspapiers der Sektion Endoskopie der DGVS, Stand 07 / 2010Capsule Endoscopy for the Diagnosis of Small Bowel DiseasesAn Updated Statement by the Endoscopy Section of DGVSA. May1 , J. Albert2 , M. Keuchel3 , G. Moog4 , D. Hartmann5
  • 1Innere Medizin II, HSK Wiesbaden, Lehrkrankenhaus der Johannes Gutenberg-Universität Mainz
  • 2Medizinische Klinik 1,Klinikum der Johann-Wolfgang-Goethe-Universität Frankfurt am Main
  • 3Klinik für Innere Medizin, Bethesda Krankenhaus Bergedorf, Hamburg, Lehrkrankenhaus der Universität Hamburg
  • 4Gastroenterologie Marienkrankenhaus, Kassel
  • 5Medizinische Klinik C, Klinikum der Stadt Ludwigshafen am Rhein, Lehrkrankenhaus der Johannes Gutenberg-Universität Mainz
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Publication History

Publication Date:
24 November 2010 (online)

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1. Einleitung

Die Kapselendoskopie hat die Dünndarmdiagnostik revolutioniert, da erstmals ein nicht invasives Verfahren zur Verfügung steht, das eine endoskopische Beurteilung der Schleimhaut ermöglicht. Optimal ergänzt wurde der klinische Einsatz der Kapselendoskopie, als mit der Einführung der Doppelballonenteroskopie ein komplementäres endoskopisches Verfahren zur Verfügung stand, das auf nicht chirurgischem Weg den Zugang zu den tieferen Dünndarmabschnitten und damit die Probenentnahme und Durchführung therapeutischer Maßnahmen ermöglichte.

In das aktuelle Update wurden nur Veröffentlichungen in Journalen mit Gutachterverfahren einbezogen. Die Literatursuche erfolgte über Medline und PubMed. Die einzelnen Abschnitte wurden jeweils von einem der Autoren verfasst (siehe Anhang), die Empfehlungen von allen Autoren gemeinsam diskutiert und festgelegt. Die Klassifizierung der Evidenz erfolgte nach Oxford Centre of Evidence Based Medicine [1] ([Tab. 1]).

Tab. 1 Klassifizierung der Evidenz- und Empfehlungsgrade 1. Empfehlungsgrad Evidenzgrad Beschreibung A Ia „Evidenz” durch systematisches Review randomisierter kontrollierter Studien (RCT) Ib „Evidenz” durch eine geeignet geplante RCT Ic Alle-oder-Keiner-Prinzip B IIa „Evidenz” durch systematisches Review gut geplanter Kohortenstudien IIb „Evidenz” durch eine gut geplante Kohortenstudie/RCT mäßiger Qualität (z. B. < 80 % Follow-up) IIc „Evidenz” durch Outcome-Research-Studien IIIa „Evidenz” durch systematisches Review gut geplanter Fallkontrollstudien IIIb „Evidenz” durch eine Fallkontrollstudie C IV „Evidenz” durch Fallserien/Kohorten- und Fallkontrollstudien mäßiger Qualität D V Expertenmeinung ohne explizite kritische Bewertung oder basierend auf physiologischen Modellen, Laborforschungsresultaten oder „first principles”

Literatur

  • 1 The Oxford Centre for Evidence-Based Medicine .Levels of evidence and grades of recommendation. Oxford; http://www.cebm.net/?o=1025 , Zugriff: 17. Mai 2010.
    Google Scholar
  • 2 Iddan G, Meron G, Glukhovsky A et al. Wireless capsule endoscopy.  Nature. 2000;  405 417
    Google Scholar
  • 3 Bandorski D, Irnich W, Brück M et al. Capsule endoscopy and cardiac pacemakers: investigation for possible interference.  Endoscopy. 2008;  40 36-39
    Google Scholar
  • 4 Bandorski D, Irnich W, Brück M et al. Do endoscopy capsules interfere with implantable cardioverter-defibrillators?.  Endoscopy. 2009;  41 457-461
    Google Scholar
  • 5 Bandorski D, Diehl K L, Jaspersen D. Capsule endoscopy in patients with cardiac pacemakers: current situation in Germany.  Z Gastroenterol. 2005;  43 715-718
    Google Scholar
  • 6 Leighton J A, Srivathsan K, Carey E J et al. Safety of wireless capsule endoscopy in patients with implantable cardiac defibrillators.  Am J Gastroenterol. 2005;  100 1728-1731
    Google Scholar
  • 7 Leighton J A, Sharma V K, Srivathsan K et al. Safety of capsule endoscopy in patients with pacemakers.  Gastrointest Endosc. 2004;  59 567-569
    Google Scholar
  • 8 Dirks M H, Costea F, Seidman E G. Successful videocapsule endoscopy in patients with an abdominal cardiac pacemaker.  Endoscopy. 2008;  40 73-75
    Google Scholar
  • 9 Dubner S, Dubner Y, Rubio H et al. Electromagnetic interference from wireless video-capsule endoscopy on implantable cardioverter-defibrillators.  Pacing Clin Electrophysiol. 2007;  30 472-475
    Google Scholar
  • 10 Holden J P, Dureja P, Pfau P R et al. Endoscopic placement of the small-bowel video capsule by using a capsule endoscope delivery device.  Gastrointest Endosc. 2007;  65 842-847
    Google Scholar
  • 11 Carey E J, Heigh R I, Fleischer D E. Endoscopic capsule endoscope delivery for patients with dysphagia, anatomical abnormalities, or gastroparesis.  Gastrointest Endosc. 2004;  59 423-426
    Google Scholar
  • 12 Albert J, Göbel C M, Lesske J et al. Simethicone for small bowel preparation for capsule endoscopy: a systematic, single-blinded, controlled study.  Gastrointest Endosc. 2004;  59 487-491
    Google Scholar
  • 13 Ge Z Z, Chen H Y, Gao Y J et al. The role of simeticone in small-bowel preparation for capsule endoscopy.  Endoscopy. 2006;  38 836-840
    Google Scholar
  • 14 Wei W, Ge Z Z, Lu H et al. Purgative bowel cleansing combined with simethicone improves capsule endoscopy imaging.  Am J Gastroenterol. 2008;  103 77-82
    Google Scholar
  • 15 Fang Y H, Chen C X, Zhang B L. Effect of small bowel preparation with simethicone on capsule endoscopy.  J Zhejiang Univ Sci B. 2009;  10 46-51
    Google Scholar
  • 16 Spada C, Riccioni M E, Familiari P et al. Polyethylene glycol plus simethicone in small-bowel preparation for capsule endoscopy.  Dig Liver Dis. 2009;  [Epub ahead of print]
    Google Scholar
  • 17 Esaki M, Matsumoto T, Kudo T et al. Bowel preparations for capsule endoscopy: a comparison between simethicone and magnesium citrate.  Gastrointest Endosc. 2009;  69 94-101
    Google Scholar
  • 18 Rokkas T, Papaxoinis K, Triantafyllou K et al. Does purgative preparation influence the diagnostic yield of small bowel video capsule endoscopy? A meta-analysis.  Am J Gastroenterol. 2009;  104 219-227
    Google Scholar
  • 19 Viazis N, Sgouros S, Papaxoinis K et al. Bowel preparation increases the diagnostic yield of capsule endoscopy: a prospective, randomized, controlled study.  Gastrointest Endosc. 2004;  60 534-538
    Google Scholar
  • 20 Ben-Soussan E, Savoye G, Antonietti M et al. Is a 2-liter PEG preparation useful before capsule endoscopy?.  J Clin Gastroenterol. 2005;  39 381-384
    Google Scholar
  • 21 Tuyl S A, den Ouden van H, Stolk M F et al. Optimal preparation for video capsule endoscopy: a prospective, randomized, single-blind study.  Endoscopy. 2007;  39 1037-1040
    Google Scholar
  • 22 Wi J, Moon J, Kim Y et al. A prospective randomized multicenter study of preparation for capsule endoscopy.  Gastrointest Endoscopy. 2006;  63 Supp S, AB M 1310, AB 168
    Google Scholar
  • 23 Lapalus M G, Ben-Soussan E, Saurin J C. Capsule endoscopy and bowel preparation with oral sodium phosphate: a prospective randomized trial. : Abstract Book p.135. In The 5th International Conference on Capsule Endoscopy. June 9 – 10, 2006. Paris;
    Google Scholar
  • 24 Niv Y, Niv G, Wiser K et al. Capsule endoscopy – comparison of two strategies of bowel preparation.  Aliment Pharmacol Ther. 2005;  22 957-962
    Google Scholar
  • 25 Niv Y, Niv G. Capsule endoscopy: role of bowel preparation in successful visualization.  Scand J Gastroenterol. 2004;  39 1005-1009
    Google Scholar
  • 26 Pons V, Gonzalez B, Gonzalez C et al.. Evaluation of different bowel preparation for the study with capsule endoscopy: a prospective, randomized, controlled study. : Abstract Book p.133. The 5th International Conference on Capsule Endoscopy. June 9 – 10, 2006. Paris;
    Google Scholar
  • 27 Dai N, Gubler C, Hengstler P et al. Improved capsule endoscopy after bowel preparation.  Gastrointest Endosc. 2005;  61 28-31
    Google Scholar
  • 28 Kalantzis C, Triantafyllou K, Papadopoulos A A et al. Effect of three bowel preparations on video-capsule endoscopy gastric and small-bowel transit time and completeness of the examination.  Scand J Gastroenterol. 2007;  42 1120-1126
    Google Scholar
  • 29 Kantianis A, Karagiannis S, Liatsos C et al. Comparison of two schemes of small bowel preparation for capsule endoscopy with polyethylene glycol: a prospective, randomized single-blind study.  Eur J Gastroenterol Hepatol. 2009;  21 1140-1144
    Google Scholar
  • 30 Leung W K, Chan F K, Fung S S et al. Effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopy.  World J Gastroenterol. 2005;  11 4865-4868
    Google Scholar
  • 31 Fireman Z, Paz D, Kopelman Y. Capsule endoscopy: improving transit time and image view.  World J Gastroenterol. 2005;  11 5863-5866
    Google Scholar
  • 32 Caddy G R, Moran L, Chong A K et al. The effect of erythromycin on video capsule endoscopy intestinal-transit time.  Gastrointest Endosc. 2006;  63 262-266
    Google Scholar
  • 33 Niv E, Bonger I, Barkay O et al. Effect of erythromycin on image quality and transit time of capsule endoscopy: a two-center study.  World J Gastroenterol. 2008;  14 2561-2565
    Google Scholar
  • 34 Hooks 3rd S B, Rutland T J, Di Palma J A. Lubiprostone neither decreases gastric and small-bowel transit time nor improves visualization of small bowel for capsule endoscopy: a double-blind, placebo-controlled study.  Gastrointest Endosc. 2009;  70 942-946
    Google Scholar
  • 35 Selby W. Complete small-bowel transit in patients undergoing capsule endoscopy: determining factors and improvement with metoclopramide.  Gastrointest Endosc. 2005;  61 80-85
    Google Scholar
  • 36 Almeida N, Figueiredo P, Freire P et al. The effect of metoclopramide in capsule enteroscopy.  Dig Dis Sci. 2010;  55 153-157
    Google Scholar
  • 37 Apostolopoulos P, Kalantzis C, Gralnek I M et al. Clinical trial: effectiveness of chewing-gum in accelerating capsule endoscopy transit time – a prospective randomized, controlled pilot study.  Aliment Pharmacol Ther. 2008;  28 405-411
    Google Scholar
  • 38 Seitz U, Soehendra N. Solving the problem of video recording gaps in capsule endoscopy of overweight patients.  Endoscopy. 2003;  35 714
    Google Scholar
  • 39 Liao Z, Li F, Li Z S. Right lateral position improves complete examination rate of capsule endoscope: a prospective randomized, controlled trial.  Endoscopy. 2008;  40 483-487
    Google Scholar
  • 40 Ell C, May A. Mid-gastrointestinal bleeding: capsule endoscopy and push-and-pull enteroscopy give rise to a new medical term.  Endoscopy. 2006;  38 73-75
    Google Scholar
  • 41 Ell C, Remke S, May A et al. The first prospective controlled trial comparing wireless capsule endoscopy with push enteroscopy in chronic gastrointestinal bleeding.  Endoscopy. 2002;  34 685-689
    Google Scholar
  • 42 Scapa E, Jacob H, Lewkowicz S et al. Initial experience of wireless-capsule endoscopy for evaluating occult gastrointestinal bleeding and suspected small bowel pathology.  Am J Gastroenterol. 2002;  97 2776-2779
    Google Scholar
  • 43 Hartmann D, Schilling D, Bolz G et al. Capsule endoscopy versus push enteroscopy in patients with occult gastrointestinal bleeding.  Z Gastroenterol. 2003;  41 377-382
    Google Scholar
  • 44 Saurin J C, Delvaux M, Gaudin J L et al. Diagnostic value of endoscopic capsule in patients with obscure digestive bleeding: blinded comparison with video push-enteroscopy.  Endoscopy. 2003;  35 576-584
    Google Scholar
  • 45 Mylonaki M, Fritscher-Ravens A, Swain P. Wireless capsule endoscopy: a comparison with push enteroscopy in patients with gastroscopy and colonoscopy negative gastrointestinal bleeding.  Gut. 2003;  52 1122-1126
    Google Scholar
  • 46 Van Gossum A, Hittelet A, Schmit A et al. A prospective comparative study of push and wireless-capsule enteroscopy in patients with obscure digestive bleeding.  Acta Gastroenterol Belg. 2003;  66 199-205
    Google Scholar
  • 47 Pennazio M, Santucci R, Rondonotti E et al. Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases.  Gastroenterology. 2004;  126 643-653
    Google Scholar
  • 48 Adler D G, Knipschield M, Gostout C. A prospective comparison of capsule endoscopy and push enteroscopy in patients with GI bleeding of obscure origin.  Gastrointest Endosc. 2004;  59 492-498
    Google Scholar
  • 49 Kraus K, Hollerbach S, Pox C et al. Diagnostic utility of capsule endoscopy in occult gastrointestinal bleeding.  Dtsch Med Wochenschr. 2004;  129 1369-1374
    Google Scholar
  • 50 Mata A, Bordas J M, Feu F et al. Wireless capsule endoscopy in patients with obscure gastrointestinal bleeding: a comparative study with push enteroscopy.  Aliment Pharmacol Ther. 2004;  20 189-194
    Google Scholar
  • 51 Fireman Z, Eliakim R, Adler S et al. Capsule endoscopy in real life: a four-centre experience of 160 consecutive patients in Israel.  Eur J Gastroenterol Hepatol. 2004;  16 927-931
    Google Scholar
  • 52 Maieron A, Hubner D, Blaha B et al. Multicenter retrospective evaluation of capsule endoscopy in clinical routine.  Endoscopy. 2004;  36 864-868
    Google Scholar
  • 53 Enns R, Go K, Chang H et al. Capsule endoscopy: a single-centre experience with the first 226 capsules.  Can J Gastroenterol. 2004;  18 555-558
    Google Scholar
  • 54 Tang S J, Christodoulou D, Zanati S et al. Wireless capsule endoscopy for obscure gastrointestinal bleeding: a single-centre, one-year experience.  Can J Gastroenterol. 2004;  18 559-565
    Google Scholar
  • 55 Rastogi A, Schoen R E, Slivka A. Diagnostic yield and clinical outcomes of capsule endoscopy.  Gastrointest Endosc. 2004;  60 959-964
    Google Scholar
  • 56 Fireman Z, Friedman S. Diagnostic yield of capsule endoscopy in obscure gastrointestinal bleeding.  Digestion. 2004;  70 201-206 Epub 2004 Dec 17
    Google Scholar
  • 57 Ge Z Z, Hu Y Yiao S. Capsule endoscopy and push enetroscopy in the diagnosis of obscure gastrointestinal bleeding.  Chinese Medical Journal. 2004;  117 1045-1049
    Google Scholar
  • 58 Selby W. Can clinical features predict the likelihood of finding abnormalities when using capsule endoscopy in patients with GI bleeding of obscure origin.  Gastrointest endosc. 2004;  59 782-787
    Google Scholar
  • 59 Kalantzis N, Papanikolaou I S, Giannakoulopoulou E et al. Capsule endoscopy, the cumulative experience from its use in 193 patients with suspected small bowel disease.  Hepatogastroenterology. 2005;  52 414-419
    Google Scholar
  • 60 Hartmann D, Schmidt H, Bolz G et al. A prospective two-center study comparing wireless capsule endoscopy with intraoperative enteroscopy in patients with obscure GI bleeding.  Gastrointest Endosc. 2005;  61 826-832
    Google Scholar
  • 61 Viazis N, Papaxoinis K, Theodoropoulos I et al. Impact of capsule endoscopy in obscure small-bowel bleeding: defining strict diagnostic criteria for a favorable outcome.  Gastrointest Endosc. 2005;  62 717-722
    Google Scholar
  • 62 Chao C C, Ng Jao Y T, Mo L R. Capsule endoscopy for gastrointestinal bleeding with an obscure etiology.  J Formos Med Assoc. 2005;  104 659-665
    Google Scholar
  • 63 Carlo J T, Demarco D, Smith B A et al. The utility of capsule endoscopy and its role for diagnosing pathology in the gastrointestinal tract.  Am J Surg. 2006;  190 886-890
    Google Scholar
  • 64 Marmo R, Rotondano G, Rondonotti E et al. Capsule enteroscopy versus other diagnostic procedures in diagnosing obscure gastrointestinal bleeding: a cost-effectiveness study.  Eur J Gastroenterol Hepatol. 2007;  19 535-542
    Google Scholar
  • 65 Albert J G, Schülbe R, Hahn L et al. Impact of capsule endoscopy on outcome in mid-intestinal bleeding: a multicentre cohort study in 285 patients.  Eur J Gastroenterol Hepatol. 2008;  20 971-977
    Google Scholar
  • 66 Sidhu R, Sanders D S, Kapur K et al. Factors predicting the dagnostic yield and intervention in obscure gastrointestinal bleeding investigated using capsule endoscopy.  J Gastrointest Liver Dis. 2009;  18 273-278
    Google Scholar
  • 67 Zhang B L, Fang Y H, Chen C X et al. Single-center experience of 309 consecutive patients with obscure gastrointestinal bleeding.  World J Gastroenterol. 2009;  15 5740-5745
    Google Scholar
  • 68 Rondotti E, Soncini M, Girelli C et al. Small bowel capsule endoscopy in clinical practice: a multicenter 7-year survey.  Eur J Gastroenterol Hepatol. 2010;  , epub
    Google Scholar
  • 69 Greve E, Moussata D, gaudin J L et al. High diagnostic and clinical impact of small bowel capsule endoscopy in patients with hereditary hemorrhagic teleangiectasiea with overt digestive bleeding and/or severe anaemia.  Gastrointest Endosc. 2010;  71 760-767
    Google Scholar
  • 70 Velayos B, Herreros de Trejada A, Fernandez L et al. Upper gastrointestinal findings detected by capsule endoscopy in obscure gastrointestinal bleeding.  Rev Esp Enferm Dig. 2009;  101 11-19
    Google Scholar
  • 71 Peter S, Heuss L T, Beglinger C et al. Capsule Endoscopy of the Upper Gastrointestinal Tract – The Need for a Second Endoscopy.  Digestion. 2005;  72 242-247
    Google Scholar
  • 72 Kitiyakara T, Selby W. Non-small-bowel lesions detected by capsule endoscopy in patients with obscure GI bleeding.  Gastrointest Endosc. 2005;  62 234-238
    Google Scholar
  • 73 Delvaux M, Fassler I, Gay G. Clinical usefullness of the endoscopic video capsule as the initial intestinal investigation in patients with obscure digestive bleeding: validation of a diagnostic strategy based on the patient outcome after 12 months.  Endoscopy. 2004;  36 1067-1073
    Google Scholar
  • 74 Lara L F, Bloomfeld R S, Pineau B C. The rate of lesions found within reach of esophagogastroduodenosopy during push enteroscopy depends on the type of obscure gastrointestinal bleeding.  Endoscopy. 2004;  36 745-750
    Google Scholar
  • 75 May A, Wardak A, Nachbar L et al. Influence of patient selection on the outcome of capsule endoscopy in patients with chronic gastrointestinal bleeding.  J Clin Gastroenterol. 2005;  39 684-688
    Google Scholar
  • 76 Bresci G, Parisi G, Bertoni M et al. The role of capsule endoscopy for evaluating obscure gastrointestinal bleeding: usefulness of early use.  J Gastroenterol. 2005;  40 256-259
    Google Scholar
  • 77 Carey E J, Leighton J A, Heigh R I et al. A single-center experience of 260 consecutive patients undergoing capsule endoscopy for obscure gastrointestinal bleeding.  Am J Gastroenterol. 2007;  102 89-95
    Google Scholar
  • 78 Apostolopoulos P, Liatsos C, Gralnek I M et al. Evaluation of capsule endoscopy in active, mild-to-moderate, overt, obscure GI bleeding.  Gastrointest Endosc. 2007;  66 1174-1181
    Google Scholar
  • 79 Almeida N, Figueiredo P, Lopes S et al. Urgent capsule endoscopy is useful in severe obscure-overt gastrointestinal bleeding.  Digestive Endoscopy. 2009;  21 87-92
    Google Scholar
  • 80 Kaffes A J, Siah C, Koo J H. Clinical outcomes after double-balloon enteroscopy in patients with obscure GI bleeding and a positive capsule endoscopy.  Gastrointest Endosc. 2007;  66 304-309
    Google Scholar
  • 81 Kamalaporn P, Cho S, Basset N et al. Double-balloon enteroscopy following capsule endoscopy in the management of obscure gastrointestinal bleeding: outcome of acombined approach.  Can J Gastroenterol. 2008;  22 491-495
    Google Scholar
  • 82 Esaki M, Matsumoto T, Yada S et al. Factors associated with clinical impact of capsule endoscopy in patients with overt obscure gastrointestinal bleeding.  Dig Dis Sci. 2009;  ; epub ahead of print
    Google Scholar
  • 83 Lewis B S, Swain P. Capsule endoscopy in the evaluation of patients with suspected small intestinal bleeding: results of a pilot study.  Gastrointest Endosc. 2002;  56 349-353
    Google Scholar
  • 84 Triester S L, Leighton J A, Leontiadis G I et al. A meta- analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding.  Am J Gastroenterol. 2005;  100 2407-2418
    Google Scholar
  • 85 Leusse A de, Vahedi K, Edery J et al. Capsule endoscopy or Push enteroscopy for the first-line exploration of obscure gastrointestinal bleeding?.  Gastroenterology. 2007;  132 855-862
    Google Scholar
  • 86 Pasha S F, Leighton J A, Das A et al. Double-balloon enteroscopy and capsule endoscopy have comparable diagnostic yield in small-bowel disease: a meta-analysis.  Clin Gastroenetrol Hepatol. 2008;  6 671-676
    Google Scholar
  • 87 Matsumoto T, Esaki M, Moriyama T et al. Comparison of capsule endoscopy and enteroscopy with the double-balloon method in patients with obscure bleeding and polyposis.  Endoscopy. 2005;  37 827-832
    Google Scholar
  • 88 Hadithi M, Heine D N, Jacobs M AJM et al. A prospective study comparing video capsule endoscopy with double-balloon enteroscopy in patients with obscure gastrointestinal bleeding.  Am J Gastroenterol. 2006;  101 52-57
    Google Scholar
  • 89 Nakamura M, Niwa Y, Ohmiya N et al. Preliminary comparison of capsule endoscopy and bouble-balloon enteroscopy in patients with small-bowel bleeding.  Endoscopy. 2006;  38 60-67
    Google Scholar
  • 90 Fujimori S, Seo T, Gudis K et al. Diagnosis and treatment of obscure gastrointestinal bleeding using combined capsule endoscopy and double balloon endoscopy: 1-year follow-up study.  Endoscopy. 2007;  39 1053 1058
    Google Scholar
  • 91 Ohmiya N, Yano T, Yamamoto H et al. Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy.  Gastrointest Endosc. 2007;  66 S72-S77
    Google Scholar
  • 92 Kameda N, Higuchi K, Shiba M et al. A prospective, single-bind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding.  J Gastroenterol. 2010;  45 468-469
    Google Scholar
  • 93 Li X, Dai J, Lu H et al. A prospective study on evaluating the diagnostic yield of videeo capsule endoscopy followed by directed double balloon enteroscopy in patients with obscure gastrointestinal bleeding.  Dig Dis Sci. 2010;  55 1704-1710
    Google Scholar
  • 94 Marmo R, Rotondano G, Casetti T et al. Degree of concordance between double-balloon enteroscopy and capsule endoscopy in obscure gastrointestinal bleeding: a multicenter study.  Endoscopy. 2009;  41 587-592
    Google Scholar
  • 95 Arakawa D, Ohmiya N, Nakamura M et al. Outcome after enteroscopy fro patients with obscure GI bleding: diagnostic comparison between double-balloon endoscopy and videocapsule endoscopy.  Gastrointest Endosc. 2009;  69 875-874
    Google Scholar
  • 96 Gay G, Delvaux M, Fassler I. Outcome of capsule Endoscopy in determining indication and route for push-and-pull enteroscopy.  Endoscopy. 2006;  38 50-59
    Google Scholar
  • 97 Costamagna G, Shah S K, Riccioni M E et al. A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease.  Gastroenterology. 2002;  123 999-1005
    Google Scholar
  • 98 Voderholzer W A, Ortner M, Rogalla P et al. Diagnostic yield of wireless capsule enteroscopy in comparison with computed tomography enteroclysis.  Endoscopy. 2003;  35 1009-1014
    Google Scholar
  • 99 Hara A K, Leighton J A, Sharma V K et al. Small bowel: preliminary comparison of capsule endoscopy with barium study and CT.  Radiology. 2004;  230 260-265
    Google Scholar
  • 100 Neu B, Ell C, May A et al. Capsule endoscopy versus standard tests in influencing management of obscure digestive bleeding: results from a German multicenter trial.  Am J Gastroenterol. 2005;  100 1736-1742
    Google Scholar
  • 101 Gölder S K, Schreyer A G, Endlicher E et al. Comparison of capsule endoscopy and magnetic resonance (MR) enteroclysis in suspected small bowel disease.  Int J Colorectal Dis. 2006;  21 97-104
    Google Scholar
  • 102 Saperas E, Dot J, Videla S et al. Capsule endoscopy versus computed tomographic or standard angiography for the diagnosis of obscure gastrointestinal bleeding.  Am J Gastroenterol. 2007;  102 731-737
    Google Scholar
  • 103 Bar-Meir S, Eliakim R, Nadler M et al. Second capsule endoscopy for patients with severe iron deficiency anaemia.  Gastrointest Endosc. 2001;  60 711-713
    Google Scholar
  • 104 Bradford H J, Fleischer D E, Sharma V K et al. Yield of repeat wireless video capsule endoscopy in patients with obscure gastrointestinal bleeding.  Am J Gastroenterol. 2005;  100 1058-1064
    Google Scholar
  • 105 Vizis N, Papaxoinis K, Vlachogiannakos J et al. Is there a role for second-look capsule endoscopy in patients with obscure gastrointestinal bleeding after a nondiagnostic first test?.  Gastrointest Endosc. 2009;  69 850-856
    Google Scholar
  • 106 Ross A, Mehdizadeh S, Tokar J. Double balloon enteroscopy detects small bowel mass lesions missed by capsule endoscopy.  Dig Dis Sci. 2008;  53 2140-2143
    Google Scholar
  • 107 Lai L, Wong G LH, Chow D KL et al. Long-term follow-up of patients with obscure gastrointestinal bleeding after negative capsule endoscopy.  Am J Gastroenterol. 2006;  101 1224-1228
    Google Scholar
  • 108 Hindryckx P, Botelberge T, Vos de M et al. Clinical impact of capsule endoscopy on further strategy and long-term clinical outcome in patients with obscure bleeding.  Gastrointest Endosc. 2008;  68 98-104
    Google Scholar
  • 109 Macdonald J, Porter V, Mc Namara D. Negatice capsule endoscopy in patients with obscure GI bleeding predicts low rebleeding rates.  Gastrointest Endosc. 2008;  68 1122-1127
    Google Scholar
  • 110 Redondo-Cerezo E, Gómez-Ruiz C J, Sánchez-Manjavacas N et al. Long-term follow-up of patients with small-bowel angiodysplasia on capsule endoscopy: determinants of a higher clinical impact and rebleeding rate.  Rev Esp Enferm Dig. 2008;  100 202-207
    Google Scholar
  • 111 Landi B, Cellier C, Gaudric M et al. Long-term outcome of patients with gastrointestinal bleeding of obscure origin explored by push enteroscopy.  Endoscopy. 2002;  34 355-359
    Google Scholar
  • 112 Laine L, Sahota A, Shah A. Does capsule endoscopy improve outcomes in obscure gastrointestinal bleeding? Randomized trial versus dedicated smallbowel radiography.  Gastroenterology. 2010;  138 1673-1680 s
    Google Scholar
  • 113 Stange E F, Travis S PL, Vermeire S et al. European evidence based consensus on the diagnosis and management of Crohn’s disease: definitions and diagnosis.  Gut. 2006;  55 (Suppl 1) i1-i15
    Google Scholar
  • 114 Stange E F, Schreiber S, Folsch U R et al. Diagnostik und Therapie des M. Crohn – Ergebnisse einer evidenzbasierten Konsensuskonferenz der Deutschen Gesellschaft fur Verdauungs- und Stoffwechselkrankheiten.  Z Gastroenterol. 2003;  41 19-20
    Google Scholar
  • 115 Dionisio P M, Gurudu S R, Leighton J A et al. Capsule Endoscopy Has a Significantly Higher Diagnostic Yield in Patients With Suspected and Established Small-Bowel Crohn’s Disease: A Meta-Analysis.  Am J Gastroenterol. 2010;  105 1240-1248
    Google Scholar
  • 116 Triester S L, Leighton J A, Leontiadis G I et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with non-stricturing small bowel Crohn’s disease.  Am J Gastroenterol. 2006;  101 954-964
    Google Scholar
  • 117 Marmo R, Rotondano G, Piscopo R et al. Meta-analysis: capsule enteroscopy vs. conventional modalities in diagnosis of small bowel diseases.  Aliment Pharmacol Ther. 2005;  22 595-604
    Google Scholar
  • 118 Leighton J A, Triester S L, Sharma V K. Capsule endoscopy: a meta-analysis for use with obscure gastrointestinal bleeding and Crohn’s disease.  Gastrointest Endosc Clin N Am. 2006;  16 229-250
    Google Scholar
  • 119 Dubcenco E, Jeejeebhoy K N, Petroniene R et al. Capsule endoscopy findings in patients with established and suspected small-bowel Crohn’s disease: correlation with radiologic, endoscopic, and histologic findings.  Gastrointest Endosc. 2005;  62 538-544
    Google Scholar
  • 120 Eliakim R, Suissa A, Yassin K et al. Wireless capsule video endoscopy compared to barium follow-through and computerised tomography in patients with suspected Crohn’s disease – final report.  Dig Liver Dis. 2004;  36 519-522
    Google Scholar
  • 121 Hara A K, Leighton J A, Heigh R I et al. Crohn disease of the small bowel: preliminary comparison among CT enterography, capsule endoscopy, small-bowel follow-through, and ileoscopy.  Radiology. 2006;  238 128-134
    Google Scholar
  • 122 Albert J G, Martiny F, Krummenerl A et al. Diagnosis of small bowel Crohn’s disease: a prospective comparison of capsule endoscopy with magnetic resonance imaging and fluoroscopic enteroclysis.  Gut. 2005;  54 1721-1727
    Google Scholar
  • 123 Voderholzer W A, Beinhoelzl J, Rogalla P et al. Small bowel involvement in Crohn’s disease: a prospective comparison of wireless capsule endoscopy and computed tomography enteroclysis.  Gut. 2005;  54 369-373
    Google Scholar
  • 124 Golder S K, Schreyer A G, Endlicher E et al. Comparison of capsule endoscopy and magnetic resonance (MR) enteroclysis in suspected small bowel disease.  Int J Colorectal Dis. 2006;  21 97-104
    Google Scholar
  • 125 Tukey M, Pleskow D, Legnani P et al. The utility of capsule endoscopy in patients with suspected Crohn’s disease.  Am J Gastroenterol. 2009;  104 2734-2739
    Google Scholar
  • 126 Bardan E, Nadler M, Chowers Y et al. Capsule endoscopy for the evaluation of patients with chronic abdominal pain.  Endoscopy. 2003;  35 688-689
    Google Scholar
  • 127 De Bona M, Bellumat A, Cian E et al. Capsule endoscopy findings in patients with suspected Crohn’s disease and biochemical markers of inflammation.  Dig Liver Dis. 2006;  38 331-335
    Google Scholar
  • 128 Valle J, Alcantara M, Perez-Grueso M J et al. Clinical features of patients with negative results from traditional diagnostic work-up and Crohn’s disease findings from capsule endoscopy.  J Clin Gastroenterol. 2006;  40 692-696
    Google Scholar
  • 129 Fry L C, Carey E J, Shiff A D et al. The yield of capsule endoscopy in patients with abdominal pain or diarrhea.  Endoscopy. 2006;  38 498-502
    Google Scholar
  • 130 Shim K, Kim Y, Kim K et al. Abdominal pain accompanied by weight loss may increase the diagnostic yield of capsule endoscopy: a Korean multicenter study.  Scand J Gastroenterol. 2006;  41 983-988
    Google Scholar
  • 131 Fidder H H, Nadler M, Lahat A et al. The utility of capsule endoscopy in the diagnosis of Crohn’s disease based on patient’s symptoms.  J Clin Gastroenterol. 2007;  41 384-387
    Google Scholar
  • 132 May A, Manner H, Schneider M et al. Prospective multicenter trial of capsule endoscopy in patients with chronic abdominal pain, diarrhea and other signs and symptoms (CEDAP-Plus Study).  Endoscopy. 2007;  39 606-612
    Google Scholar
  • 133 Sidhu R, Sanders D S, Morris A J et al. Guidelines on small bowel enteroscopy and capsule endoscopy in adults.  Gut. 2008;  57 125-136
    Google Scholar
  • 134 Oshitani N, Yukawa T, Yamagami H et al. Evaluation of deep small bowel involvement by double-balloon enteroscopy in Crohn’s disease.  Am J Gastroenterol. 2006;  101 1484-1489
    Google Scholar
  • 135 Pohl J, May A, Nachbar L et al. Diagnostic and therapeutic yield of push-and-pull enteroscopy for symptomatic small bowel Crohn’s disease strictures.  Eur J Gastroenterol Hepatol. 2007;  19 529-534
    Google Scholar
  • 136 Bourreille A, Ignjatovic A, Aabakken L et al. Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED-ECCO consensus.  Endoscopy. 2009;  41 618-637
    Google Scholar
  • 137 Maunoury V, Savoye G, Bourreille A et al. Value of wireless capsule endoscopy in patients with indeterminate colitis (inflammatory bowel disease type unclassified).  Inflamm Bowel Dis. 2007;  13 152-155
    Google Scholar
  • 138 Mehdizadeh S, Chen G, Enayati P J et al. Diagnostic yield of capsule endoscopy in ulcerative colitis and inflammatory bowel disease of unclassified type (IBDU).  Endoscopy. 2008;  40 30-35
    Google Scholar
  • 139 Murrell Z, Vasiliauskas E, Melmed G et al. Preoperative wireless capsule endoscopy does not predict outcome after ileal pouch-anal anastomosis.  Dis Colon Rectum. 2010;  53 293-300
    Google Scholar
  • 140 Bousvaros A, Antonioli D A, Colletti R B et al. Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn’s and Colitis Foundation of America.  J Pediatr Gastroenterol Nutr. 2007;  44 653-674
    Google Scholar
  • 141 Pons Beltran V, Nos P, Bastida G et al. Evaluation of postsurgical recurrence in Crohn’s disease: a new indication for capsule endoscopy?.  Gastrointest Endosc. 2007;  66 533-540
    Google Scholar
  • 142 Biancone L, Calabrese E, Petruzziello C et al. Wireless capsule endoscopy and small intestine contrast ultrasonography in recurrence of Crohn’s disease.  Inflamm Bowel Dis. 2007;  13 1256-1265
    Google Scholar
  • 143 Bourreille A, Jarry M, D’Halluin P N et al. Wireless capsule endoscopy versus ileocolonoscopy for the diagnosis of postoperative recurrence of Crohn’s disease: a prospective study.  Gut. 2006;  55 978-983
    Google Scholar
  • 144 Regueiro M, Schraut W, Baidoo L et al. Infliximab prevents Crohn’s disease recurrence after ileal resection.  Gastroenterology. 2009;  136 441-450.e1 quiz 716
    Google Scholar
  • 145 Efthymiou A, Viazis N, Mantzaris G et al. Does clinical response correlate with mucosal healing in patients with Crohn’s disease of the small bowel? A prospective, case-series study using wireless capsule endoscopy.  Inflamm Bowel Dis. 2008;  14 1542-1547
    Google Scholar
  • 146 Goldfarb N I, Pizzi L T, Fuhr J PJ et al. Diagnosing Crohn’s disease: an economic analysis comparing wireless capsule endoscopy with traditional diagnostic procedures.  Dis Manag. 2004;  7 292-304
    Google Scholar
  • 147 Moy L, Levine J. Wireless capsule endoscopy in the pediatric age group: experience and complications.  J Pediatr Gastroenterol Nutr. 2007;  44 516-520
    Google Scholar
  • 148 Arguelles-Arias F, Caunedo A, Romero J et al. The value of capsule endoscopy in pediatric patients with a suspicion of Crohn’s disease.  Endoscopy. 2004;  36 869-873
    Google Scholar
  • 149 Cohen S A, Gralnek I M, Ephrath H et al. Capsule endoscopy may reclassify pediatric inflammatory bowel disease: a historical analysis.  J Pediatr Gastroenterol Nutr. 2008;  47 31-36
    Google Scholar
  • 150 Moy L, Levine J. Capsule endoscopy in the evaluation of patients with unexplained growth failure.  J Pediatr Gastroenterol Nutr. 2009;  48 647-650
    Google Scholar
  • 151 Fritscher-Ravens A, Scherbakov P, Bufler P et al. The feasibility of wireless capsule endoscopy in detecting small intestinal pathology in children under the age of 8 years: a multicentre European study.  Gut. 2009;  58 1467-1472
    Google Scholar
  • 152 Atay O, Mahajan L, Kay M et al. Risk of capsule endoscope retention in pediatric patients: a large single-center experience and review of the literature.  J Pediatr Gastroenterol Nutr. 2009;  49 196-201
    Google Scholar
  • 153 Cheifetz A S, Kornbluth A A, Legnani P et al. The risk of retention of the capsule endoscope in patients with known or suspected Crohn’s disease.  Am J Gastroenterol. 2006;  101 2218-2222
    Google Scholar
  • 154 Chong A KH, Taylor A, Miller A et al. Capsule endoscopy vs. push enteroscopy and enteroclysis in suspected small-bowel Crohn’s disease.  Gastrointest Endosc. 2005;  61 255-261
    Google Scholar
  • 155 Liao Z, Gao R, Xu C et al. Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review.  Gastrointest Endosc. 2010;  71 280-286
    Google Scholar
  • 156 Li F, Gurudu S R, De Petris G et al. Retention of the capsule endoscope: a single-center experience of 1000 capsule endoscopy procedures.  Gastrointest Endosc. 2008;  68 174-180
    Google Scholar
  • 157 Postgate A J, Burling D, Gupta A et al. Safety, Reliability and Limitations of the Given Patency Capsule in Patients at Risk of Capsule Retention: A 3-Year Technical Review.  Dig Dis Sci. 2008;  53 2732-2738
    Google Scholar
  • 158 Signorelli C, Rondonotti E, Villa F et al. Use of the Given Patency System for the screening of patients at high risk for capsule retention.  Dig Liver Dis. 2006;  38 326-330
    Google Scholar
  • 159 Spada C, Riccioni M E, Costamagna G. The new, dissolving patency capsule: a safe and effective tool to avoid the complication of retained video capsules.  J Clin Gastroenterol. 2008;  42 761-762
    Google Scholar
  • 160 Delvaux M, Ben Soussan E, Laurent V et al. Clinical evaluation of the use of the M 2A patency capsule system before a capsule endoscopy procedure, in patients with known or suspected intestinal stenosis.  Endoscopy. 2005;  37 801-807
    Google Scholar
  • 161 Herrerias J M, Leighton J A, Costamagna G et al. Agile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy.  Gastrointest Endosc. 2008;  67 902-909
    Google Scholar
  • 162 Buchman A L, Miller F H, Wallin A et al. Videocapsule endoscopy versus barium contrast studies for the diagnosis of Crohn’s disease recurrence involving the small intestine.  Am J Gastroenterol. 2004;  99 2171-2177
    Google Scholar
  • 163 Marmo R, Rotondano G, Piscopo R et al. Capsule endoscopy versus enteroclysis in the detection of small-bowel involvement in Crohn’s disease: a prospective trial.  Clin Gastroenterol Hepatol. 2005;  3 772-776
    Google Scholar
  • 164 Efthymiou A, Viazis N, Vlachogiannakos J et al. Wireless capsule endoscopy versus enteroclysis in the diagnosis of small-bowel Crohn’s disease.  Eur J Gastroenterol Hepatol. 2009;  21 866-871
    Google Scholar
  • 165 Giardiello F M, Welsh S B, Hamilton S R et al. Increased risk of cancer in the Peutz-Jeghers syndrome.  N Engl J Med. 1987;  316 1511-1514
    Google Scholar
  • 166 Schulmann K, Hollerbach S, Kraus K et al. Feasibility and diagnostic utility of video capsule endoscopy for the detection of small bowel polyps in patients with hereditary polyposis syndromes.  Am J Gastroenterol. 2005;  100 27-37
    Google Scholar
  • 167 Soares J, Lopes L, Vilas B G et al. Wireless capsule endoscopy for evaluation of phenotypic expression of small-bowel polyps in patients with Peutz-Jeghers syndrome and in symptomatic first-degree relatives.  Endoscopy. 2004;  36 1060-1066
    Google Scholar
  • 168 Caspari R, Falkenhausen von M, Krautmacher C et al. Comparison of capsule endoscopy and magnetic resonance imaging for the detection of polyps of the small intestine in patients with familial adenomatous polyposis or with Peutz-Jeghers’ syndrome.  Endoscopy. 2004;  36 1054-1059
    Google Scholar
  • 169 Brown G, Fraser C, Schofield G et al. Video capsule endoscopy in peutz-jeghers syndrome: a blinded comparison with barium follow-through for detection of small-bowel polyps.  Endoscopy. 2006;  38 385-390
    Google Scholar
  • 170 Postgate A, Hyer W, Phillips R et al. Feasibility of video capsule endoscopy in the management of children with Peutz-Jeghers syndrome: a blinded comparison with barium enterography for the detection of small bowel polyps.  J Pediatr Gastroenterol Nutr. 2009;  49 417-423
    Google Scholar
  • 171 Galle T S, Juel K, Bulow S. Causes of death in familial adenomatous polyposis.  Scand J Gastroenterol. 1999;  34 808-812
    Google Scholar
  • 172 Spigelman A D, Williams C B, Talbot I C et al. Upper gastrointestinal cancer in patients with familial adenomatous polyposis.  Lancet. 1989;  2 783-785
    Google Scholar
  • 173 Iaquinto G, Fornasarig M, Quaia M et al. Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis.  Gastrointest Endosc. 2008;  67 61-67
    Google Scholar
  • 174 Burke C A, Santisi J, Church J et al. The utility of capsule endoscopy small bowel surveillance in patients with polyposis.  Am J Gastroenterol. 2005;  100 1498-1502
    Google Scholar
  • 175 Katsinelos P, Kountouras J, Chatzimavroudis G et al. Wireless capsule endoscopy in detecting small-intestinal polyps in familial adenomatous polyposis.  World J Gastroenterol. 2009;  15 6075-6079
    Google Scholar
  • 176 Schulz A C, Bojarski C, Buhr H J et al. Occurrence of adenomas in the pouch and small intestine of FAP patients after proctocolectomy with ileoanal pouch construction.  Int J Colorectal Dis. 2008;  23 437-441
    Google Scholar
  • 177 Plum N, May A, Manner H et al. Small-bowel diagnosis in patients with familial adenomatous polyposis: comparison of push enteroscopy, capsule endoscopy, ileoscopy, and enteroclysis.  Z Gastroenterol. 2009;  47 339-346
    Google Scholar
  • 178 Tescher P, Macrae F A, Speer T et al. Surveillance of FAP: a prospective blinded comparison of capsule endoscopy and other GI imaging to detect small bowel polyps.  Hered Cancer Clin Pract. 2010;  8 3
    Google Scholar
  • 179 Wong R F, Tuteja A K, Haslem D S et al. Video capsule endoscopy compared with standard endoscopy for the evaluation of small-bowel polyps in persons with familial adenomatous polyposis (with video).  Gastrointest Endosc. 2006;  64 530-537
    Google Scholar
  • 180 Riemann J F, Hartmann D, Schilling D et al. Frequency of small bowel polyps in patients with duodenal adenoma but without familial adenomatous polyposis.  Z Gastroenterol. 2006;  44 235-238
    Google Scholar
  • 181 Baichi M M, Arifuddin R M, Mantry P S. Metachronous small bowel adenocarcinomas detected by capsule endoscopy in a patient with hereditary nonpolyposis colorectal cancer.  Dig Dis Sci. 2007;  52 1134-1136
    Google Scholar
  • 182 Marmo R, Rotondano G, Riccio G et al. Small-bowel adenocarcinoma diagnosed via capsule endoscopy in a patient found to have hereditary nonpolyposis colorectal cancer.  Gastrointest Endosc. 2007;  65 524-525, discussion
    Google Scholar
  • 183 Saurin J C, Pilleul F, Soussan E B et al. and the Capsule Commission of the French Society of Digestive Endoscopy (SFED). Small-bowel capsule endoscopy diagnoses early and advanced neoplasms in asymptomatic patients with Lynch syndrome.  Published ahead of print Endoscopy. 2010;  42 1-6
    Google Scholar
  • 184 Postgate A J, Will O C, Fraser C H et al. Capsule endoscopy for the small bowel in juvenile polyposis syndrome: a case series.  Endoscopy. 2009;  41 1001-1004
    Google Scholar
  • 185 Perez-Segura P, Siso I, Luque R et al. Iatrogenic intestinal obstruction: a rare complication of capsule endoscopy in a patient with familial adenomatous polyposis.  Endoscopy. 2007;  39 (Suppl 1) E298-E299
    Google Scholar
  • 186 Ersoy O, Akin E, Ugras S et al. Capsule endoscopy findings in celiac disease.  Dig Dis Sci. 2009;  54 825-829
    Google Scholar
  • 187 Hopper A D, Sidhu R, Hurlstone D P et al. Capsule endoscopy: an alternative to duodenal biopsy for the recognition of villous atrophy in coeliac disease?.  Dig Liver Dis. 2007;  39 140-145
    Google Scholar
  • 188 Petroniene R, Dubcenco E, Baker J P et al. Given capsule endoscopy in celiac disease: evaluation of diagnostic accuracy and interobserver agreement.  Am J Gastroenterol. 2005;  100 685-694
    Google Scholar
  • 189 Rondonotti E, Spada C, Cave D et al. Video capsule enteroscopy in the diagnosis of celiac disease: a multicenter study.  Am J Gastroenterol. 2007;  102 1624-1631
    Google Scholar
  • 190 El-Matary W, Huynh H, Vandermeer B. Diagnostic characteristics of given video capsule endoscopy in diagnosis of celiac disease: a meta-analysis.  J Laparoendosc Adv Surg Tech A. 2009;  19 815-820
    Google Scholar
  • 191 Biagi F, Rondonotti E, Campanella J et al. Video capsule endoscopy and histology for small-bowel mucosa evaluation: a comparison performed by blinded observers.  Clin Gastroenterol Hepatol. 2006;  4 998-1003
    Google Scholar
  • 192 Murray J A, Rubio-Tapia A, Van Dyke C T et al. Mucosal atrophy in celiac disease: extent of involvement, correlation with clinical presentation, and response to treatment.  Clin Gastroenterol Hepatol. 2008;  6 186-193
    Google Scholar
  • 193 Maiden L, Elliott T, McLaughlin S D et al. A blinded pilot comparison of capsule endoscopy and small bowel histology in unresponsive celiac disease.  Dig Dis Sci. 2009;  54 1280-1283
    Google Scholar
  • 194 Culliford A, Daly J, Diamond B et al. The value of wireless capsule endoscopy in patients with complicated celiac disease.  Gastrointest Endosc. 2005;  62 55-61
    Google Scholar
  • 195 Daum S, Wahnschaffe U, Glasenapp R et al. Capsule endoscopy in refractory celiac disease.  Endoscopy. 2007;  39 455-458
    Google Scholar
  • 196 Kakugawa Y, Kim S W, Takizawa K et al. Small intestinal CMV disease detected by capsule endoscopy after allogeneic hematopoietic SCT.  Bone Marrow Transplant. 2008;  42 283-284
    Google Scholar
  • 197 Reddy D N, Sriram P V, Rao G V et al. Capsule endoscopy appearances of small-bowel tuberculosis.  Endoscopy. 2003;  35 99
    Google Scholar
  • 198 Cello J P. Capsule endoscopy features of human immunodeficiency virus and geographical diseases.  Gastrointest Endosc Clin N Am. 2004;  14 169-177
    Google Scholar
  • 199 Soares J, Lopes L, Villas-Boas G et al. Ascariasis observed by wireless-capsule endoscopy.  Endoscopy. 2003;  35 194
    Google Scholar
  • 200 Barnett K, Emder P, Day A S et al. Tapeworm infestation: a cause of iron deficiency anemia shown by capsule endoscopy.  Gastrointest Endosc. 2007;  66 625-627
    Google Scholar
  • 201 Liatsos C, Goulas S, Karagiannis S et al. Diagnosis of small-bowel ischemic necrosis by capsule endoscopy.  Gastrointest Endosc. 2005;  62 439-440
    Google Scholar
  • 202 Tsibouris P, Kalantzis C, Alexandrakis G et al. Capsule endoscopy findings in a case of intestinal sarcoidosis.  Endoscopy. 2009;  41 (Suppl 2) E191
    Google Scholar
  • 203 Endo H, Kondo Y, Kawagoe K et al. Lupus enteritis detected by capsule endoscopy.  Intern Med. 2007;  46 1621-1622
    Google Scholar
  • 204 Liatsos C, Kyriakos N, Vasilakos I et al. Diffuse enteric ischemia due to Wegener’s granulomatosis revealed by capsule endoscopy (with video).  Endoscopy. 2010;  42 (Suppl 2) E39
    Google Scholar
  • 205 Koumi A, Panos M Z. A new capsule endoscopy feature of serosal eosinophilic enteritis.  Endoscopy. 2009;  41 (Suppl 2) E280
    Google Scholar
  • 206 Rivet C, Lapalus M G, Dumortier J et al. Use of capsule endoscopy in children with primary intestinal lymphangiectasia.  Gastrointest Endosc. 2006;  64 649-650
    Google Scholar
  • 207 Danielsson A, Toth E, Thorlacius H. Capsule endoscopy in the management of a patient with a rare syndrome – yellow nail syndrome with intestinal lymphangiectasia.  Gut. 2006;  55 196, 233
    Google Scholar
  • 208 Johanssen S, Boivin M, Lochs H et al. The yield of wireless capsule endoscopy in the detection of neuroendocrine tumors in comparison with CT enteroclysis.  Gastrointest Endosc. 2006;  63 660-665
    Google Scholar
  • 209 Tuyl S A, Noorden van J T, Timmer van R et al. Detection of small-bowel neuroendocrine tumors by video capsule endoscopy.  Gastrointest Endosc. 2006;  64 66-72
    Google Scholar
  • 210 Flieger D, Keller R, May A et al. Capsule endoscopy in gastrointestinal lymphomas.  Endoscopy. 2005;  37 1174-1180
    Google Scholar
  • 211 Prakoso E, Selby W S. Capsule endoscopy in patients with malignant melanoma.  Am J Gastroenterol. 2007;  102 1204-1208
    Google Scholar
  • 212 Yakoub-Agha I, Maunoury V, Wacrenier A et al. Impact of Small Bowel Exploration Using Video-Capsule Endoscopy in the Management of Acute Gastrointestinal Graft-versus-Host Disease.  Transplantation. 2004;  78 1697-1701
    Google Scholar
  • 213 Franchis de R, Rondonotti E, Abbiati C et al. Capsule enteroscopy in small bowel transplantation.  Dig Liver Dis. 2003;  35 728-731
    Google Scholar
  • 214 Goldstein J L, Eisen G M, Lewis B et al. Small bowel mucosal injury is reduced in healthy subjects treated with celecoxib compared with ibuprofen plus omeprazole, as assessed by video capsule endoscopy.  Aliment Pharmacol Ther. 2007;  25 1211-1222
    Google Scholar
  • 215 Hawkey C J, Ell C, Simon B et al. Less small-bowel injury with lumiracoxib compared with naproxen plus omeprazole.  Clin Gastroenterol Hepatol. 2008;  6 536-544
    Google Scholar
  • 216 Maiden L, Thjodleifsson B, Theodors A et al. A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy.  Gastroenterology. 2005;  128 1172-1178
    Google Scholar
  • 217 Antao B, Bishop J, Shawis R et al. Clinical application and diagnostic yield of wireless capsule endoscopy in children.  J Laparoendosc Adv Surg Tech A. 2007;  17 364-370
    Google Scholar
  • 218 Thomson M, Fritscher-Ravens A, Mylonaki M et al. Wireless capsule endoscopy in children: a study to assess diagnostic yield in small bowel disease in paediatric patients.  J Pediatr Gastroenterol Nutr. 2007;  44 192-197
    Google Scholar
  • 219 Guilhonde Araujo Sant’Anna A M, Dubois J, Miron M C et al. Wireless capsule endoscopy for obscure small-bowel disorders: final results of the first pediatric controlled trial.  Clin Gastroenterol Hepatol. 2005;  3 264-270
    Google Scholar
  • 220 Mata A, Bordas J M, Feu F et al. Wireless capsule endoscopy in patients with obscure gastrointestinal bleeding: a comparative study with push enteroscopy.  Alimentary Pharmacology and Therapeutics. 2004;  20 189-194
    Google Scholar
  • 221 Gay G, Deluaux M, Laurent V et al. Temporary intestinal occlusion induced by a patency capsule in a patient with Crohn’s disease.  Endoscopy. 2005;  37 174-177
    Google Scholar

PD Dr. Dirk Hartmann

Medizinische Klinik C, Klinikum Ludwigshafen gGmbH

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67063 Ludwigshafen

Phone: ++ 49/6 21/5 03 41 61

Fax: ++ 49/6 21/5 03 41 14

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