Planta Med 2000; 66(1): 80-81
DOI: 10.1055/s-0029-1243116
Letter

© Georg Thieme Verlag Stuttgart · New York

Furoquinolines with Antiplatelet Aggregation Activity from Leaves of Melicope confusa

Keh-Shaw Chen1 , Ya-Ling Chang2 , Che-Ming Teng2 , Chieh-Fu Chen3 , Yang-Chang Wu3 , 4 ,*
  • 1Ta-Jen Pharmaceutical Junior College, Ping Tung Hsien, Taiwan
  • 2Pharmacological Institute, College of Medicine, National Taiwan University, Taipei, Taiwan
  • 3National Research Institute of Chinese Medicine, Taipei, Taiwan
  • 4Graduate Institute of Natural Products, Kaohsiung Medical College, Kaohsiung, Taiwan
Further Information

Publication History

Received: May 6, 1999

Accepted: June 12, 1999

Publication Date:
24 November 2009 (online)

Abstract

Using antiplatelet aggregation as a guide for fractionation, four furoquinoline-type alkaloids, confusameline (1), skimmianine (2), kokusaginine (3), and O-methylconfusameline (4), were isolated from the leaves of Melicope confusa. All compounds showed significant antiplatelet aggregation activity.

References

Prof. Yang-Chang Wu

Graduate Institute of Natural Products

Kaohsiung Medical University

Kaohsiung 807

Taiwan

Email: yachwu@cc.kmc.edu.tw

Fax: +886-7-3114773

Phone: +886-7-3121101 ext. 2197