Osteoplastie in Kombination mit der Radiofrequenzablation zur palliativen Therapie schmerzhafter osteolytischer Knochenmetastasen

Zusammenfassung

Die perkutane Vertebroplastie und Osteoplastie sind minimalinvasive palliative Therapieverfahren, bei welchen unter radiologischer Kontrolle Knochenzement in eine schmerzhafte osteolytische Knochenmetastase eingebracht wird. Neben der palliativen Schmerztherapie kommt der Stabilisierung frakturierter Knochen und Wirbelkörper eine entscheidende Bedeutung zu. Zur lokalen Metastasenbehandlung wird die Methode zunehmend erfolgreich mit der Radiofrequenzablation (RFA) kombiniert eingesetzt.

Summary

Osteolytic metastases are a challenging problem in cancer patients. Moreover, these patients are increasing because primary tumours are well controlled by recent advances in primary cancer treatments. Nevertheless, pain relief and bone stabilization are the priorities for most cancer patients with painful bone metastases and pathological vertebral fractures. Until now, treatments for bone metastases have been mainly conservative, such as radiation therapy, chemotherapy, or analgetics. Additionally vertebroplasty and osteoplasty has been widely used in these patients. Recently, a new technique that combines RF ablation therapy followed by percutaneous cement injection has shown to be effective when bone metastases become bulky, extend outside bones or in metastastic lesions with epidural extension and cortical disruption.

Schlüsselwörter

Vertebroplastie - Osteoplastie - Knochenmetastasen - ossäre Metastasen - RFA - palliative Therapie

Keywords

Vertebroplasty - Osteoplasty - Bone metatstases - RFA - Radiofrequency ablation - Palliative care

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