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Synfacts 2010(3): 0273-0273  
DOI: 10.1055/s-0029-1219252
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of (+)-Neopeltolide

Contributor(s): Steven V. Ley, Philippa B. Cranwell
X. Guinchard, E. Roulland*
Centre de Recherche CNRS de Gif-sur-Yvette, France
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Publication History

Publication Date:
18 February 2010 (online)

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Significance

(+)-Neopeltolide is a marine macrocycle which was isolated in 2006 from a sponge of the Neopeltidae family. It has activity against various cancer cell lines including lung adenocarcinoma and also shows activity against fungal pathogens, for example Candida albicans.