Synlett 2010(1): 163-164  
DOI: 10.1055/s-0029-1219038
SPOTLIGHT
© Georg Thieme Verlag Stuttgart ˙ New York

9-Amino-9-Deoxyepicinchona Alkaloids

Qiao-Feng Wang
Research Center for Chirotechnology, Fourth Military Medical University (FMMU), Xi’an 710032, P. R. of China
e-Mail: zytwqf@fmmu.edu.cn;
Further Information

Publication History

Publication Date:
14 December 2009 (online)

Introduction

9-Amino-9-deoxyepicinchona alkaloids constitute the newest generation of the family of cinchona alkaloids. The last few years have witnessed a special interest in this kind of cinchona alkaloids derivatives. [¹] As bifunctional organocatalysts combine a Brønsted acid and Lewis base in one molecule, they are capable of promoting many asymmetric reactions and provide access to chiral building blocks of high enantiopurity. In addition, they can be easily prepared in one pot from inexpensive alkaloid starting materials in either of pseudo-enantiomeric forms (Scheme  [¹] ). [²]

Scheme 1

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