Synthesis 2009(16): 2785-2789  
DOI: 10.1055/s-0029-1216876
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Copper(I)-Catalyzed Caryl-Calkynyl Bond Formation of Aryl Iodides with Terminal Alkynes

K. G. Thakur, G. Sekar*
Department of Chemistry, Indian Institute of Technology Madras, Chennai, Tamil Nadu 600036, India
Fax: +91(44)22574202; e-Mail: gsekar@iitm.ac.in;
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Publikationsverlauf

Received 6 April 2009
Publikationsdatum:
26. Juni 2009 (online)

Abstract

A wide range of internal alkynes are synthesized from the corresponding aryl iodides and terminal alkynes by Sonogashira­-type cross-coupling reactions through Caryl-Calkynyl bond formation in the presence of a catalytic amount of readily available DBU-CuBr complex under mild reaction conditions.